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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 227.5
Min nTPM: 49.8
Std nTPM: 29.0
Median nTPM:
153_1
70 years, female
227.5
377_1
82 years, female
189.0
246_1
77 years, male
174.3
425_1
59 years, female
173.3
229_1
69 years, female
172.6
189_1
76 years, male
164.8
163_1
78 years, male
161.5
9_1
66 years, female
160.9
162_1
79 years, female
158.0
115_1
83 years, male
157.2
18_1
88 years, male
157.0
266_1
85 years, male
153.5
126_1
63 years, male
153.1
243_1
75 years, male
150.1
352_1
62 years, male
147.5
177_1
74 years, male
147.4
405_1
91 years, male
144.9
406_1
79 years, male
144.1
172_1
72 years, female
143.5
217_1
76 years, male
143.2
414_1
84 years, female
142.7
321_1
62 years, female
141.1
6_1
73 years, female
139.1
109_1
81 years, female
138.3
319_1
81 years, male
136.5
237_1
82 years, male
135.7
468_1
89 years, male
135.6
142_1
61 years, female
134.9
376_1
75 years, female
130.9
81_1
67 years, male
127.7
394_1
75 years, female
127.7
404_1
82 years, female
127.6
322_1
76 years, male
127.3
286_1
68 years, female
127.1
2_1
77 years, female
125.2
503_1
68 years, male
125.0
318_1
68 years, male
123.1
335_1
73 years, female
122.5
324_1
76 years, male
122.0
526_1
61 years, male
122.0
316_1
62 years, male
121.5
313_1
79 years, female
121.4
499_1
55 years, female
121.1
375_1
74 years, female
120.1
349_1
83 years, male
119.6
35_1
74 years, female
118.8
4_1
88 years, female
118.7
518_1
75 years, female
118.5
117_1
61 years, male
118.4
517_1
88 years, male
118.0
89_1
63 years, male
115.8
265_1
87 years, male
114.4
480_1
63 years, male
114.4
293_1
68 years, female
113.6
355_1
70 years, female
113.2
218_1
71 years, female
112.7
350_1
84 years, female
111.7
396_1
62 years, male
111.5
264_1
73 years, female
110.3
32_1
67 years, male
109.8
415_1
77 years, female
109.5
42_1
85 years, male
109.2
413_1
59 years, female
108.2
145_1
84 years, male
106.2
466_1
57 years, female
105.8
291_1
76 years, male
105.5
139_1
64 years, female
104.4
99_1
64 years, male
103.9
251_1
78 years, male
103.8
386_1
76 years, male
103.4
320_1
89 years, female
103.2
17_1
71 years, male
102.9
389_1
86 years, female
102.8
292_1
71 years, male
102.1
506_1
65 years, male
100.4
254_1
77 years, female
100.3
501_1
88 years, male
99.3
311_1
78 years, male
98.9
351_1
91 years, male
96.2
149_1
88 years, male
95.3
137_1
83 years, male
94.3
356_1
87 years, female
94.0
354_1
81 years, female
93.8
288_1
66 years, female
93.6
315_1
62 years, female
93.6
379_1
60 years, male
92.2
353_1
82 years, female
90.4
307_1
66 years, female
90.0
173_1
67 years, male
89.4
452_1
88 years, female
88.8
120_1
70 years, female
88.7
308_1
70 years, female
88.4
490_1
67 years, female
87.8
384_1
83 years, male
87.1
447_1
81 years, male
86.4
43_1
64 years, female
84.5
348_1
84 years, male
83.4
119_1
70 years, female
80.0
347_1
72 years, male
78.7
495_1
57 years, female
78.3
295_1
61 years, female
69.1
41_1
94 years, female
68.1
317_1
60 years, male
65.4
491_1
89 years, female
54.6
314_1
67 years, male
49.8
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
