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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:77.0 nTPM
HPA:77.0 nTPM
GTEx:504.2 nTPM
FANTOM5:171.5 Scaled Tags Per Million
Pig:919.0 nTPM
Mouse:612.6 nTPM
Allen mouse:0.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 77.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 2.8
2019 Male, age 18, unknown 16.7
2666 Male, age 74, left hemisphere 12.1
1827 Male, age 72, unknown 0.0
1830 Male, age 51, unknown 0.0
1833 Male, age 53, unknown 0.0
1870 Female, age 42, unknown 0.0
2219 Male, age 76, both hemispheres 0.0
2411 Female, age 72, unknown 0.0
2586 Male, age 75, left hemisphere 0.0
2828 Female, age 72, unknown 0.0
Dorsal raphe nucleus
nTPM: 0.0
1828 Male, age 53, unknown 0.0
2016 Female, age 72, unknown 0.0
2047 Male, age 72, unknown 0.0
2298 Female, age 72, unknown 0.0
2750 Male, age 76, both hemispheres 0.0
Inferior colliculus
nTPM: 0.0
1848 Female, age 42, unknown 0.0
1890 Male, age 53, unknown 0.0
2097 Female, age 72, unknown 0.0
2849 Male, age 72, unknown 0.0
Median raphe nucleus
nTPM: 2.7
2220 Male, age 76, midline 2.7
Pedunculopontine tegmental nucleus
nTPM: 6.9
2334 Male, age 80, both hemispheres 20.9
1921 Female, age 85, both hemispheres 0.0
2338 Male, age 61, both hemispheres 0.0
Periaquaductal grey, anterior
nTPM: 0.0
1795 Male, age 51, unknown 0.0
1947 Male, age 18, unknown 0.0
2502 Female, age 75, unknown 0.0
Periaquaductal grey, dorsal
nTPM: 0.0
1831 Male, age 72, unknown 0.0
1840 Male, age 53, unknown 0.0
2464 Female, age 72, unknown 0.0
2850 Male, age 76, both hemispheres 0.0
Periaquaductal grey, lateral
nTPM: 0.0
2053 Male, age 18, unknown 0.0
2140 Male, age 76, both hemispheres 0.0
2272 Male, age 74, both hemispheres 0.0
Pretectal area
nTPM: 77.0
1817 Female, age 42, unknown 209.5
1816 Male, age 51, unknown 192.6
1944 Female, age 72, unknown 190.7
2007 Male, age 72, unknown 186.1
1815 Male, age 53, unknown 68.6
2224 Female, age 72, unknown 0.0
2273 Male, age 74, both hemispheres 0.0
2316 Male, age 76, right hemisphere 0.0
2407 Male, age 75, both hemispheres 0.0
2667 Female, age 75, unknown 0.0
2825 Male, age 18, unknown 0.0
Red nucleus
nTPM: 0.3
2785 Male, age 18, unknown 4.2
1821 Female, age 72, unknown 0.0
1865 Male, age 51, unknown 0.0
1904 Male, age 53, unknown 0.0
1954 Female, age 42, unknown 0.0
2227 Male, age 72, unknown 0.0
2503 Female, age 72, unknown 0.0
2584 Male, age 75, left hemisphere 0.0
2588 Male, age 74, left hemisphere 0.0
2725 Female, age 75, unknown 0.0
2769 Male, age 72, unknown 0.0
2823 Male, age 76, right hemisphere 0.0
Substantia nigra
nTPM: 32.3
1889 Female, age 72, unknown 122.9
1941 Male, age 53, unknown 89.1
1916 Female, age 42, unknown 59.7
2665 Male, age 74, both hemispheres 51.3
1851 Male, age 51, unknown 0.0
2241 Male, age 72, unknown 0.0
2409 Female, age 72, unknown 0.0
2583 Male, age 75, right hemisphere 0.0
2590 Female, age 75, unknown 0.0
2699 Male, age 18, unknown 0.0
Superior colliculus
nTPM: 14.9
2087 Female, age 72, unknown 97.0
2668 Female, age 75, unknown 51.9
1796 Male, age 53, unknown 0.0
1839 Male, age 51, unknown 0.0
1895 Male, age 76, right hemisphere 0.0
1913 Female, age 42, unknown 0.0
1995 Male, age 72, unknown 0.0
2261 Male, age 18, unknown 0.0
2587 Male, age 74, left hemisphere 0.0
2664 Male, age 75, both hemispheres 0.0
Ventral tegmental area
nTPM: 1.0
2218 Male, age 76, both hemispheres 6.0
1915 Female, age 42, unknown 0.0
1942 Male, age 51, unknown 0.0
2021 Male, age 53, unknown 0.0
2223 Female, age 72, unknown 0.0
2410 Female, age 72, unknown 0.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 504.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 504.2
Samples: 139

Max nTPM: 1966.2
Min nTPM: 177.9
Std nTPM: 290.5
Median nTPM: 404.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1966.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1664.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1335.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1275.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1224.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1016.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1011.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1006.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1003.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 982.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 943.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 937.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 930.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 881.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 859.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 837.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 835.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 820.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 819.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 789.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 779.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 772.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 755.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 750.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 744.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 736.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 713.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 690.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 684.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 679.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 664.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 662.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 659.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 646.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 638.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 632.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 603.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 590.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 588.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 588.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 576.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 574.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 573.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 568.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 561.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 553.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 552.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 545.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 537.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 534.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 509.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 504.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 501.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 480.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 478.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 473.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 454.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 449.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 449.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 448.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 445.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 438.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 437.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 436.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 429.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 426.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 424.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 413.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 407.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 404.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 401.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 399.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 388.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 388.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 387.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 378.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 378.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 377.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 376.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 373.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 364.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 359.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 356.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 351.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 346.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 343.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 343.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 341.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 340.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 340.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 335.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 334.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 334.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 330.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 329.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 326.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 325.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 323.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 322.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 317.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 317.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 311.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 311.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 307.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 307.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 302.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 301.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 301.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 295.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 289.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 285.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 283.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 272.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 271.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 270.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 267.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 265.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 264.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 264.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 261.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 257.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 254.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 253.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 252.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 251.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 251.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 251.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 244.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 241.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 232.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 232.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 230.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 230.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 229.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 225.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 208.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 189.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 179.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 177.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 171.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 171.5
FF:10158-103A5 76 years, female 171.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 919.0
Pig sample Sample description nTPM
Midbrain
nTPM: 833.8
Samples: 4

Max nTPM: 1225.8
Min nTPM: 556.5
Sample A Female 556.5
Sample B Female 579.0
Sample C Male 1225.8
Sample D Male 973.8
Periaqueductal gray
nTPM: 578.6
Samples: 3

Max nTPM: 701.6
Min nTPM: 483.9
Sample B Female 550.4
Sample C Male 701.6
Sample D Male 483.9
Substantia nigra
nTPM: 627.6
Samples: 4

Max nTPM: 875.2
Min nTPM: 351.4
Sample A Female 875.2
Sample B Female 450.3
Sample C Male 833.5
Sample D Male 351.4
Superior colliculi
nTPM: 919.0
Samples: 4

Max nTPM: 1161.9
Min nTPM: 466.1
Sample A Female 1096.0
Sample B Female 466.1
Sample C Male 1161.9
Sample D Male 952.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 612.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 612.6
Samples: 4

Max nTPM: 630.0
Min nTPM: 597.4
Sample A Male 630.0
Sample B Male 597.4
Sample C Female 605.4
Sample D Female 617.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.9
184 Antisense, RP_Baylor_102654, Mouse strain C57BL/6J (56 days, male) 0.9

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