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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:447.0 nTPM
HPA:447.0 nTPM
GTEx:439.7 nTPM
FANTOM5:388.9 Scaled Tags Per Million
Pig:122.8 nTPM
Mouse:12.9 nTPM
Allen mouse:1.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 447.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 400.0
2411 Female, age 72, unknown 423.4
1870 Female, age 42, unknown 422.7
2586 Male, age 75, left hemisphere 412.5
1830 Male, age 51, unknown 412.4
1833 Male, age 53, unknown 410.9
2019 Male, age 18, unknown 410.3
2828 Female, age 72, unknown 395.2
2219 Male, age 76, both hemispheres 385.5
1827 Male, age 72, unknown 374.7
2666 Male, age 74, left hemisphere 352.8
Dorsal raphe nucleus
nTPM: 403.4
2750 Male, age 76, both hemispheres 449.9
1828 Male, age 53, unknown 409.4
2047 Male, age 72, unknown 406.2
2016 Female, age 72, unknown 389.2
2298 Female, age 72, unknown 362.6
Inferior colliculus
nTPM: 401.6
1848 Female, age 42, unknown 421.0
1890 Male, age 53, unknown 407.0
2849 Male, age 72, unknown 389.9
2097 Female, age 72, unknown 388.6
Median raphe nucleus
nTPM: 367.2
2220 Male, age 76, midline 367.2
Pedunculopontine tegmental nucleus
nTPM: 392.2
2334 Male, age 80, both hemispheres 404.2
1921 Female, age 85, both hemispheres 390.1
2338 Male, age 61, both hemispheres 382.4
Periaquaductal grey, anterior
nTPM: 375.1
2502 Female, age 75, unknown 390.4
1947 Male, age 18, unknown 374.9
1795 Male, age 51, unknown 360.0
Periaquaductal grey, dorsal
nTPM: 367.5
2464 Female, age 72, unknown 394.3
1840 Male, age 53, unknown 369.1
2850 Male, age 76, both hemispheres 357.8
1831 Male, age 72, unknown 348.7
Periaquaductal grey, lateral
nTPM: 367.7
2053 Male, age 18, unknown 380.7
2272 Male, age 74, both hemispheres 362.6
2140 Male, age 76, both hemispheres 359.9
Pretectal area
nTPM: 384.0
1817 Female, age 42, unknown 419.6
2316 Male, age 76, right hemisphere 407.3
2667 Female, age 75, unknown 401.9
1815 Male, age 53, unknown 396.2
2007 Male, age 72, unknown 379.1
2224 Female, age 72, unknown 376.1
2825 Male, age 18, unknown 375.1
1944 Female, age 72, unknown 373.7
1816 Male, age 51, unknown 371.5
2273 Male, age 74, both hemispheres 368.0
2407 Male, age 75, both hemispheres 355.7
Red nucleus
nTPM: 447.0
1821 Female, age 72, unknown 483.1
1904 Male, age 53, unknown 480.3
1865 Male, age 51, unknown 477.8
1954 Female, age 42, unknown 476.2
2227 Male, age 72, unknown 475.4
2769 Male, age 72, unknown 474.8
2823 Male, age 76, right hemisphere 459.6
2503 Female, age 72, unknown 449.9
2588 Male, age 74, left hemisphere 430.0
2785 Male, age 18, unknown 413.3
2725 Female, age 75, unknown 381.8
2584 Male, age 75, left hemisphere 361.9
Substantia nigra
nTPM: 388.1
2699 Male, age 18, unknown 412.7
1889 Female, age 72, unknown 403.5
1851 Male, age 51, unknown 401.5
1916 Female, age 42, unknown 396.4
2241 Male, age 72, unknown 391.5
2409 Female, age 72, unknown 389.8
2590 Female, age 75, unknown 385.8
2583 Male, age 75, right hemisphere 382.2
1941 Male, age 53, unknown 359.3
2665 Male, age 74, both hemispheres 358.7
Superior colliculus
nTPM: 387.6
1895 Male, age 76, right hemisphere 434.8
2668 Female, age 75, unknown 402.3
1913 Female, age 42, unknown 399.0
1995 Male, age 72, unknown 395.4
1839 Male, age 51, unknown 389.2
2587 Male, age 74, left hemisphere 387.5
2087 Female, age 72, unknown 378.8
1796 Male, age 53, unknown 367.2
2261 Male, age 18, unknown 366.7
2664 Male, age 75, both hemispheres 354.6
Ventral tegmental area
nTPM: 394.2
2410 Female, age 72, unknown 424.3
2223 Female, age 72, unknown 421.9
1915 Female, age 42, unknown 391.1
2021 Male, age 53, unknown 379.0
2218 Male, age 76, both hemispheres 378.3
1942 Male, age 51, unknown 370.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 439.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 439.7
Samples: 139

Max nTPM: 1062.7
Min nTPM: 169.1
Std nTPM: 146.6
Median nTPM: 413.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1062.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 831.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 790.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 776.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 733.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 715.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 708.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 692.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 685.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 675.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 671.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 665.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 650.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 630.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 630.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 629.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 620.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 606.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 602.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 594.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 592.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 588.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 584.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 571.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 570.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 568.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 568.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 557.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 556.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 549.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 549.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 548.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 546.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 543.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 531.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 527.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 522.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 511.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 511.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 507.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 504.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 498.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 493.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 492.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 491.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 486.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 481.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 479.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 477.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 473.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 469.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 469.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 467.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 466.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 461.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 458.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 458.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 451.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 447.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 440.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 436.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 436.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 430.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 423.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 422.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 420.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 417.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 414.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 413.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 413.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 410.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 403.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 402.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 401.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 401.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 399.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 397.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 396.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 396.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 390.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 388.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 384.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 383.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 382.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 380.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 375.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 374.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 371.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 370.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 368.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 365.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 365.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 358.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 357.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 355.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 354.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 350.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 350.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 348.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 348.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 346.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 344.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 340.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 339.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 335.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 330.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 327.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 324.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 322.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 321.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 314.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 313.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 311.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 308.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 306.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 305.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 303.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 300.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 297.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 292.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 291.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 291.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 288.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 279.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 274.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 273.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 266.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 262.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 259.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 253.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 242.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 234.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 234.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 229.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 229.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 228.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 207.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 201.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 169.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 388.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 388.9
FF:10158-103A5 76 years, female 388.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 122.8
Pig sample Sample description nTPM
Midbrain
nTPM: 113.5
Samples: 4

Max nTPM: 146.6
Min nTPM: 91.2
Sample A Female 146.6
Sample B Female 119.0
Sample C Male 97.0
Sample D Male 91.2
Periaqueductal gray
nTPM: 122.8
Samples: 3

Max nTPM: 133.9
Min nTPM: 103.9
Sample B Female 133.9
Sample C Male 130.5
Sample D Male 103.9
Substantia nigra
nTPM: 117.7
Samples: 4

Max nTPM: 135.8
Min nTPM: 98.7
Sample A Female 135.8
Sample B Female 98.7
Sample C Male 107.2
Sample D Male 128.9
Superior colliculi
nTPM: 110.5
Samples: 4

Max nTPM: 129.9
Min nTPM: 101.4
Sample A Female 129.9
Sample B Female 104.4
Sample C Male 106.3
Sample D Male 101.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 12.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 12.9
Samples: 4

Max nTPM: 13.3
Min nTPM: 11.7
Sample A Male 11.7
Sample B Male 13.3
Sample C Female 13.3
Sample D Female 13.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.4
68321650 Antisense, RP_041130_02_H01, Mouse strain C57BL/6J (56 days, male) 1.4

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