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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:563.9 nTPM
HPA:563.9 nTPM
GTEx:870.4 nTPM
FANTOM5:864.0 Scaled Tags Per Million
Pig:224.5 nTPM
Mouse:133.4 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 563.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 484.8
2586 Male, age 75, left hemisphere 616.7
2828 Female, age 72, unknown 585.2
1870 Female, age 42, unknown 504.0
1833 Male, age 53, unknown 501.3
1830 Male, age 51, unknown 491.9
2411 Female, age 72, unknown 481.9
2019 Male, age 18, unknown 443.0
1827 Male, age 72, unknown 438.5
2666 Male, age 74, left hemisphere 418.1
2219 Male, age 76, both hemispheres 367.2
Dorsal raphe nucleus
nTPM: 443.6
2750 Male, age 76, both hemispheres 475.3
2016 Female, age 72, unknown 467.3
1828 Male, age 53, unknown 454.3
2047 Male, age 72, unknown 414.7
2298 Female, age 72, unknown 406.5
Inferior colliculus
nTPM: 429.2
1848 Female, age 42, unknown 448.8
2849 Male, age 72, unknown 436.8
1890 Male, age 53, unknown 436.6
2097 Female, age 72, unknown 394.5
Median raphe nucleus
nTPM: 373.7
2220 Male, age 76, midline 373.7
Pedunculopontine tegmental nucleus
nTPM: 405.3
2334 Male, age 80, both hemispheres 434.7
1921 Female, age 85, both hemispheres 409.0
2338 Male, age 61, both hemispheres 372.1
Periaquaductal grey, anterior
nTPM: 414.6
2502 Female, age 75, unknown 423.9
1947 Male, age 18, unknown 412.7
1795 Male, age 51, unknown 407.1
Periaquaductal grey, dorsal
nTPM: 415.3
2464 Female, age 72, unknown 446.5
2850 Male, age 76, both hemispheres 416.8
1831 Male, age 72, unknown 401.9
1840 Male, age 53, unknown 396.0
Periaquaductal grey, lateral
nTPM: 420.0
2053 Male, age 18, unknown 449.8
2140 Male, age 76, both hemispheres 422.5
2272 Male, age 74, both hemispheres 387.6
Pretectal area
nTPM: 417.0
1815 Male, age 53, unknown 449.8
2825 Male, age 18, unknown 449.6
2316 Male, age 76, right hemisphere 449.5
2667 Female, age 75, unknown 444.6
1817 Female, age 42, unknown 434.3
2407 Male, age 75, both hemispheres 425.0
1944 Female, age 72, unknown 395.9
2273 Male, age 74, both hemispheres 393.6
2224 Female, age 72, unknown 389.0
2007 Male, age 72, unknown 382.9
1816 Male, age 51, unknown 372.3
Red nucleus
nTPM: 563.9
2769 Male, age 72, unknown 651.2
2823 Male, age 76, right hemisphere 617.7
2227 Male, age 72, unknown 607.5
1865 Male, age 51, unknown 597.5
1904 Male, age 53, unknown 587.0
1954 Female, age 42, unknown 584.2
2503 Female, age 72, unknown 573.0
1821 Female, age 72, unknown 567.8
2588 Male, age 74, left hemisphere 528.9
2725 Female, age 75, unknown 515.7
2785 Male, age 18, unknown 502.2
2584 Male, age 75, left hemisphere 433.7
Substantia nigra
nTPM: 443.6
2699 Male, age 18, unknown 511.8
2583 Male, age 75, right hemisphere 500.7
1851 Male, age 51, unknown 476.9
1916 Female, age 42, unknown 445.1
2409 Female, age 72, unknown 435.3
2665 Male, age 74, both hemispheres 433.6
2590 Female, age 75, unknown 431.5
1889 Female, age 72, unknown 428.1
2241 Male, age 72, unknown 389.9
1941 Male, age 53, unknown 382.7
Superior colliculus
nTPM: 459.4
1995 Male, age 72, unknown 553.5
1913 Female, age 42, unknown 510.2
2664 Male, age 75, both hemispheres 463.8
1796 Male, age 53, unknown 459.2
2668 Female, age 75, unknown 455.5
1895 Male, age 76, right hemisphere 452.0
1839 Male, age 51, unknown 451.1
2587 Male, age 74, left hemisphere 436.4
2087 Female, age 72, unknown 408.9
2261 Male, age 18, unknown 403.0
Ventral tegmental area
nTPM: 445.7
2223 Female, age 72, unknown 468.4
1915 Female, age 42, unknown 460.9
2410 Female, age 72, unknown 459.0
1942 Male, age 51, unknown 438.8
2021 Male, age 53, unknown 433.7
2218 Male, age 76, both hemispheres 413.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 870.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 870.4
Samples: 139

Max nTPM: 2209.9
Min nTPM: 194.5
Std nTPM: 349.1
Median nTPM: 811.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2209.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 2011.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1622.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1561.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1541.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1536.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1494.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1491.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1450.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1437.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1415.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1403.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1383.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1369.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1336.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1334.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1321.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1283.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1255.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1246.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1204.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1191.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1175.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1173.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1173.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1161.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1142.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1141.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1127.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1120.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1119.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1106.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1100.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1086.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1074.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1060.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1050.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1048.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1047.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1047.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1044.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1043.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1035.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1029.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1029.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1028.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1018.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 997.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 971.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 959.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 955.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 953.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 944.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 937.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 926.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 917.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 911.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 910.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 909.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 903.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 897.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 889.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 884.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 872.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 864.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 852.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 833.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 829.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 823.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 811.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 801.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 795.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 792.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 785.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 780.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 771.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 768.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 763.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 754.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 746.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 744.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 726.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 722.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 720.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 718.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 718.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 717.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 709.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 702.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 697.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 696.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 692.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 681.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 670.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 667.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 667.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 660.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 660.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 659.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 650.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 649.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 640.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 631.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 630.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 630.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 599.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 594.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 588.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 586.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 582.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 581.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 571.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 566.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 561.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 560.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 553.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 547.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 535.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 528.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 528.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 523.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 515.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 510.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 504.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 502.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 465.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 444.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 438.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 431.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 428.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 416.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 406.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 351.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 343.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 340.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 272.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 270.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 269.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 194.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 864.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 864.0
FF:10158-103A5 76 years, female 864.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 224.5
Pig sample Sample description nTPM
Midbrain
nTPM: 224.5
Samples: 4

Max nTPM: 396.4
Min nTPM: 137.7
Sample A Female 396.4
Sample B Female 224.3
Sample C Male 139.7
Sample D Male 137.7
Periaqueductal gray
nTPM: 161.6
Samples: 3

Max nTPM: 185.5
Min nTPM: 147.9
Sample B Female 185.5
Sample C Male 151.4
Sample D Male 147.9
Substantia nigra
nTPM: 216.2
Samples: 4

Max nTPM: 278.1
Min nTPM: 166.3
Sample A Female 238.0
Sample B Female 166.3
Sample C Male 182.4
Sample D Male 278.1
Superior colliculi
nTPM: 185.3
Samples: 4

Max nTPM: 241.1
Min nTPM: 110.8
Sample A Female 241.1
Sample B Female 110.8
Sample C Male 177.2
Sample D Male 212.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 133.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 133.4
Samples: 4

Max nTPM: 157.5
Min nTPM: 111.5
Sample A Male 157.5
Sample B Male 116.6
Sample C Female 111.5
Sample D Female 147.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
1465 Antisense, RP_040420_01_D05, Mouse strain C57BL/6J (56 days, male) 6.1
1464 Antisense, RP_040420_01_D05, Mouse strain C57BL/6J (56 days, male) 2.1
74581363 Antisense, RP_060215_03_B02, Mouse strain C57BL/6J (56 days, male) 0.1

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