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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:955.6 nTPM
HPA:955.6 nTPM
GTEx:858.1 nTPM
FANTOM5:241.2 Scaled Tags Per Million
Pig:25.4 nTPM
Mouse:419.3 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 955.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 932.1
2666 Male, age 74, left hemisphere 949.2
2019 Male, age 18, unknown 944.4
1870 Female, age 42, unknown 941.9
1827 Male, age 72, unknown 937.3
2411 Female, age 72, unknown 937.0
2219 Male, age 76, both hemispheres 926.4
1830 Male, age 51, unknown 924.2
1833 Male, age 53, unknown 923.6
2586 Male, age 75, left hemisphere 920.2
2828 Female, age 72, unknown 917.2
Dorsal raphe nucleus
nTPM: 923.6
2750 Male, age 76, both hemispheres 936.1
1828 Male, age 53, unknown 934.3
2047 Male, age 72, unknown 922.3
2298 Female, age 72, unknown 915.8
2016 Female, age 72, unknown 909.6
Inferior colliculus
nTPM: 920.0
2849 Male, age 72, unknown 926.9
1890 Male, age 53, unknown 924.1
2097 Female, age 72, unknown 919.6
1848 Female, age 42, unknown 909.6
Median raphe nucleus
nTPM: 942.1
2220 Male, age 76, midline 942.1
Pedunculopontine tegmental nucleus
nTPM: 954.5
2338 Male, age 61, both hemispheres 968.5
2334 Male, age 80, both hemispheres 949.4
1921 Female, age 85, both hemispheres 945.6
Periaquaductal grey, anterior
nTPM: 919.5
1947 Male, age 18, unknown 923.5
2502 Female, age 75, unknown 919.6
1795 Male, age 51, unknown 915.3
Periaquaductal grey, dorsal
nTPM: 904.1
2850 Male, age 76, both hemispheres 925.6
1831 Male, age 72, unknown 906.8
1840 Male, age 53, unknown 896.1
2464 Female, age 72, unknown 888.0
Periaquaductal grey, lateral
nTPM: 906.9
2053 Male, age 18, unknown 916.3
2272 Male, age 74, both hemispheres 905.0
2140 Male, age 76, both hemispheres 899.3
Pretectal area
nTPM: 933.6
1817 Female, age 42, unknown 963.3
2007 Male, age 72, unknown 961.2
1944 Female, age 72, unknown 953.0
1816 Male, age 51, unknown 945.2
1815 Male, age 53, unknown 944.3
2667 Female, age 75, unknown 928.3
2407 Male, age 75, both hemispheres 920.7
2825 Male, age 18, unknown 920.5
2224 Female, age 72, unknown 919.9
2273 Male, age 74, both hemispheres 906.7
2316 Male, age 76, right hemisphere 906.6
Red nucleus
nTPM: 955.6
2503 Female, age 72, unknown 986.1
1821 Female, age 72, unknown 980.7
2725 Female, age 75, unknown 980.6
1865 Male, age 51, unknown 977.9
1904 Male, age 53, unknown 950.0
2588 Male, age 74, left hemisphere 948.6
2785 Male, age 18, unknown 945.1
2823 Male, age 76, right hemisphere 943.3
1954 Female, age 42, unknown 942.9
2769 Male, age 72, unknown 942.7
2227 Male, age 72, unknown 941.7
2584 Male, age 75, left hemisphere 928.0
Substantia nigra
nTPM: 943.8
1916 Female, age 42, unknown 987.2
1941 Male, age 53, unknown 954.8
1889 Female, age 72, unknown 953.0
2699 Male, age 18, unknown 951.9
1851 Male, age 51, unknown 949.3
2665 Male, age 74, both hemispheres 942.9
2590 Female, age 75, unknown 931.3
2409 Female, age 72, unknown 926.2
2583 Male, age 75, right hemisphere 925.8
2241 Male, age 72, unknown 915.2
Superior colliculus
nTPM: 926.3
2587 Male, age 74, left hemisphere 961.7
1895 Male, age 76, right hemisphere 941.4
1796 Male, age 53, unknown 930.4
1995 Male, age 72, unknown 930.4
1913 Female, age 42, unknown 927.7
2668 Female, age 75, unknown 919.7
2087 Female, age 72, unknown 919.4
1839 Male, age 51, unknown 916.9
2261 Male, age 18, unknown 910.2
2664 Male, age 75, both hemispheres 904.9
Ventral tegmental area
nTPM: 929.5
2223 Female, age 72, unknown 949.5
1915 Female, age 42, unknown 947.7
2218 Male, age 76, both hemispheres 939.7
2410 Female, age 72, unknown 917.1
1942 Male, age 51, unknown 914.6
2021 Male, age 53, unknown 908.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 858.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 858.1
Samples: 139

Max nTPM: 2560.6
Min nTPM: 398.6
Std nTPM: 287.2
Median nTPM: 806.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2560.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2224.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1527.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1456.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1350.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1345.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1331.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1290.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1289.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1283.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1229.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1199.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1189.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1168.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1163.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1142.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1135.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1130.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1123.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1111.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1107.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1097.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1090.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1084.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1082.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1038.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1036.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1010.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1004.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 995.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 974.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 973.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 970.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 962.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 954.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 954.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 945.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 941.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 940.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 936.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 932.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 924.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 924.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 919.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 907.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 903.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 897.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 888.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 885.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 883.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 879.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 877.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 868.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 864.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 859.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 858.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 858.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 846.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 846.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 843.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 838.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 836.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 834.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 833.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 831.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 829.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 816.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 813.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 807.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 806.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 804.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 801.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 799.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 796.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 784.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 784.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 782.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 779.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 777.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 774.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 773.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 765.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 763.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 760.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 758.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 755.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 753.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 751.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 750.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 738.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 736.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 736.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 733.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 731.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 723.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 716.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 713.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 713.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 713.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 704.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 696.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 693.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 683.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 680.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 678.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 677.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 672.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 666.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 664.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 662.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 659.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 655.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 650.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 650.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 647.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 628.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 625.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 617.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 614.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 611.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 605.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 604.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 596.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 593.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 587.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 586.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 560.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 549.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 541.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 537.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 533.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 525.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 519.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 508.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 504.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 492.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 482.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 466.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 398.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 241.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 241.2
FF:10158-103A5 76 years, female 241.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 25.4
Pig sample Sample description nTPM
Midbrain
nTPM: 24.1
Samples: 4

Max nTPM: 25.6
Min nTPM: 22.8
Sample A Female 23.6
Sample B Female 25.6
Sample C Male 24.5
Sample D Male 22.8
Periaqueductal gray
nTPM: 22.2
Samples: 3

Max nTPM: 25.2
Min nTPM: 19.0
Sample B Female 22.3
Sample C Male 25.2
Sample D Male 19.0
Substantia nigra
nTPM: 22.6
Samples: 4

Max nTPM: 33.1
Min nTPM: 13.7
Sample A Female 33.1
Sample B Female 19.3
Sample C Male 24.4
Sample D Male 13.7
Superior colliculi
nTPM: 25.4
Samples: 4

Max nTPM: 32.9
Min nTPM: 15.8
Sample A Female 32.9
Sample B Female 15.8
Sample C Male 30.2
Sample D Male 22.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 419.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 419.3
Samples: 4

Max nTPM: 488.6
Min nTPM: 368.6
Sample A Male 488.6
Sample B Male 418.0
Sample C Female 368.6
Sample D Female 402.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
74426449 Antisense, RP_051121_02_B10, Mouse strain C57BL/6J (56 days, male) 1.6

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