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ARL6IP1
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:197.8 nTPM
HPA:197.8 nTPM
GTEx:199.7 nTPM
FANTOM5:162.9 Scaled Tags Per Million
Pig:53.1 nTPM
Mouse:311.1 nTPM
Allen mouse:13.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 197.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 178.2
1827 Male, age 72, unknown 196.3
2411 Female, age 72, unknown 193.9
1870 Female, age 42, unknown 180.5
2019 Male, age 18, unknown 177.7
2219 Male, age 76, both hemispheres 174.5
2666 Male, age 74, left hemisphere 173.4
1833 Male, age 53, unknown 172.8
2828 Female, age 72, unknown 172.2
2586 Male, age 75, left hemisphere 172.1
1830 Male, age 51, unknown 168.0
Dorsal raphe nucleus
nTPM: 189.7
2298 Female, age 72, unknown 209.7
2047 Male, age 72, unknown 199.1
1828 Male, age 53, unknown 183.0
2750 Male, age 76, both hemispheres 182.5
2016 Female, age 72, unknown 174.0
Inferior colliculus
nTPM: 181.4
2097 Female, age 72, unknown 198.3
1848 Female, age 42, unknown 182.8
1890 Male, age 53, unknown 173.5
2849 Male, age 72, unknown 171.2
Median raphe nucleus
nTPM: 197.8
2220 Male, age 76, midline 197.8
Pedunculopontine tegmental nucleus
nTPM: 181.7
1921 Female, age 85, both hemispheres 193.1
2334 Male, age 80, both hemispheres 183.0
2338 Male, age 61, both hemispheres 169.1
Periaquaductal grey, anterior
nTPM: 184.8
1947 Male, age 18, unknown 193.4
1795 Male, age 51, unknown 181.4
2502 Female, age 75, unknown 179.5
Periaquaductal grey, dorsal
nTPM: 176.6
1840 Male, age 53, unknown 185.8
2464 Female, age 72, unknown 175.8
2850 Male, age 76, both hemispheres 174.3
1831 Male, age 72, unknown 170.5
Periaquaductal grey, lateral
nTPM: 169.4
2272 Male, age 74, both hemispheres 172.3
2053 Male, age 18, unknown 170.9
2140 Male, age 76, both hemispheres 164.9
Pretectal area
nTPM: 187.4
1816 Male, age 51, unknown 204.5
1817 Female, age 42, unknown 201.7
1944 Female, age 72, unknown 198.7
2007 Male, age 72, unknown 197.7
2224 Female, age 72, unknown 196.0
1815 Male, age 53, unknown 191.7
2667 Female, age 75, unknown 187.5
2273 Male, age 74, both hemispheres 185.5
2825 Male, age 18, unknown 173.3
2407 Male, age 75, both hemispheres 164.2
2316 Male, age 76, right hemisphere 160.9
Red nucleus
nTPM: 166.6
1821 Female, age 72, unknown 185.7
2725 Female, age 75, unknown 179.5
2785 Male, age 18, unknown 172.9
2503 Female, age 72, unknown 170.9
1954 Female, age 42, unknown 167.9
2588 Male, age 74, left hemisphere 163.6
2823 Male, age 76, right hemisphere 161.7
2584 Male, age 75, left hemisphere 161.6
1904 Male, age 53, unknown 160.2
1865 Male, age 51, unknown 159.8
2227 Male, age 72, unknown 158.0
2769 Male, age 72, unknown 157.3
Substantia nigra
nTPM: 190.9
2241 Male, age 72, unknown 214.0
1916 Female, age 42, unknown 209.9
1941 Male, age 53, unknown 202.7
1889 Female, age 72, unknown 202.1
1851 Male, age 51, unknown 197.5
2409 Female, age 72, unknown 185.4
2699 Male, age 18, unknown 178.3
2590 Female, age 75, unknown 176.5
2665 Male, age 74, both hemispheres 171.8
2583 Male, age 75, right hemisphere 170.6
Superior colliculus
nTPM: 175.2
1796 Male, age 53, unknown 189.9
2087 Female, age 72, unknown 186.9
2261 Male, age 18, unknown 180.6
1895 Male, age 76, right hemisphere 176.6
2668 Female, age 75, unknown 176.2
2587 Male, age 74, left hemisphere 175.0
1839 Male, age 51, unknown 174.8
2664 Male, age 75, both hemispheres 169.1
1913 Female, age 42, unknown 163.1
1995 Male, age 72, unknown 160.0
Ventral tegmental area
nTPM: 186.5
2410 Female, age 72, unknown 199.1
1915 Female, age 42, unknown 198.5
2218 Male, age 76, both hemispheres 185.6
1942 Male, age 51, unknown 185.1
2223 Female, age 72, unknown 178.9
2021 Male, age 53, unknown 171.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 199.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 199.7
Samples: 139

Max nTPM: 403.0
Min nTPM: 94.5
Std nTPM: 63.3
Median nTPM: 190.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 403.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 388.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 368.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 357.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 334.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 333.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 323.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 321.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 320.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 311.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 310.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 302.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 298.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 283.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 276.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 275.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 274.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 269.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 263.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 262.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 261.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 259.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 257.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 257.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 255.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 255.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 253.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 245.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 242.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 240.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 240.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 239.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 238.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 235.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 233.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 232.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 230.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 227.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 227.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 226.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 225.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 224.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 223.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 221.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 218.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 217.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 216.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 213.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 213.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 211.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 210.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 210.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 208.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 208.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 208.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 208.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 207.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 206.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 205.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 205.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 204.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 204.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 202.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 201.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 198.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 198.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 196.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 194.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 191.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 190.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 188.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 187.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 187.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 186.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 185.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 185.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 182.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 182.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 180.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 177.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 176.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 176.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 176.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 174.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 174.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 173.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 172.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 172.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 172.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 170.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 170.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 170.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 169.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 167.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 165.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 165.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 164.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 164.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 163.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 163.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 162.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 160.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 159.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 158.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 158.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 157.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 157.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 154.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 153.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 150.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 150.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 149.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 148.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 148.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 146.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 145.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 141.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 134.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 132.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 131.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 130.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 129.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 127.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 125.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 123.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 122.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 118.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 114.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 112.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 112.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 110.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 109.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 106.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 102.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 98.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 95.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 95.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 95.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 94.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 162.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 162.9
FF:10158-103A5 76 years, female 162.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 53.1
Pig sample Sample description nTPM
Midbrain
nTPM: 53.1
Samples: 4

Max nTPM: 58.7
Min nTPM: 48.2
Sample A Female 48.2
Sample B Female 48.3
Sample C Male 58.7
Sample D Male 57.2
Periaqueductal gray
nTPM: 50.9
Samples: 3

Max nTPM: 62.2
Min nTPM: 42.1
Sample B Female 48.4
Sample C Male 62.2
Sample D Male 42.1
Substantia nigra
nTPM: 47.1
Samples: 4

Max nTPM: 60.8
Min nTPM: 33.7
Sample A Female 60.8
Sample B Female 41.5
Sample C Male 52.5
Sample D Male 33.7
Superior colliculi
nTPM: 50.9
Samples: 4

Max nTPM: 58.9
Min nTPM: 42.8
Sample A Female 58.9
Sample B Female 42.8
Sample C Male 54.6
Sample D Male 47.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 311.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 311.1
Samples: 4

Max nTPM: 315.6
Min nTPM: 301.2
Sample A Male 301.2
Sample B Male 312.1
Sample C Female 315.5
Sample D Female 315.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 13.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.2
69526874 Antisense, RP_050421_01_G10, Mouse strain C57BL/6J (56 days, male) 13.2

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