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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:260.8 nTPM
HPA:260.8 nTPM
GTEx:156.5 nTPM
FANTOM5:666.0 Scaled Tags Per Million
Pig:19.4 nTPM
Mouse:593.5 nTPM
Allen mouse:13.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 260.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 235.4
2019 Male, age 18, unknown 257.1
1827 Male, age 72, unknown 245.7
2411 Female, age 72, unknown 242.2
2828 Female, age 72, unknown 239.0
1870 Female, age 42, unknown 238.9
2666 Male, age 74, left hemisphere 237.5
2586 Male, age 75, left hemisphere 230.2
1830 Male, age 51, unknown 222.9
1833 Male, age 53, unknown 221.1
2219 Male, age 76, both hemispheres 219.0
Dorsal raphe nucleus
nTPM: 224.7
2298 Female, age 72, unknown 245.6
2016 Female, age 72, unknown 227.7
2750 Male, age 76, both hemispheres 225.2
1828 Male, age 53, unknown 217.6
2047 Male, age 72, unknown 207.6
Inferior colliculus
nTPM: 236.0
2097 Female, age 72, unknown 262.7
1848 Female, age 42, unknown 233.7
2849 Male, age 72, unknown 224.8
1890 Male, age 53, unknown 222.9
Median raphe nucleus
nTPM: 220.5
2220 Male, age 76, midline 220.5
Pedunculopontine tegmental nucleus
nTPM: 222.5
2334 Male, age 80, both hemispheres 230.1
1921 Female, age 85, both hemispheres 227.4
2338 Male, age 61, both hemispheres 209.9
Periaquaductal grey, anterior
nTPM: 248.0
2502 Female, age 75, unknown 255.6
1795 Male, age 51, unknown 253.1
1947 Male, age 18, unknown 235.2
Periaquaductal grey, dorsal
nTPM: 231.1
1840 Male, age 53, unknown 236.6
2464 Female, age 72, unknown 236.2
2850 Male, age 76, both hemispheres 228.9
1831 Male, age 72, unknown 222.6
Periaquaductal grey, lateral
nTPM: 234.4
2272 Male, age 74, both hemispheres 248.5
2053 Male, age 18, unknown 235.2
2140 Male, age 76, both hemispheres 219.6
Pretectal area
nTPM: 260.8
1816 Male, age 51, unknown 290.7
1817 Female, age 42, unknown 286.4
2007 Male, age 72, unknown 283.1
1944 Female, age 72, unknown 282.4
1815 Male, age 53, unknown 274.8
2273 Male, age 74, both hemispheres 268.9
2667 Female, age 75, unknown 264.2
2224 Female, age 72, unknown 244.7
2407 Male, age 75, both hemispheres 229.4
2825 Male, age 18, unknown 227.7
2316 Male, age 76, right hemisphere 216.2
Red nucleus
nTPM: 227.2
2785 Male, age 18, unknown 253.2
1821 Female, age 72, unknown 244.0
1865 Male, age 51, unknown 233.0
2503 Female, age 72, unknown 230.6
1954 Female, age 42, unknown 229.7
2725 Female, age 75, unknown 227.1
2227 Male, age 72, unknown 225.9
2769 Male, age 72, unknown 225.4
1904 Male, age 53, unknown 224.7
2823 Male, age 76, right hemisphere 216.8
2588 Male, age 74, left hemisphere 208.2
2584 Male, age 75, left hemisphere 207.3
Substantia nigra
nTPM: 226.6
1889 Female, age 72, unknown 260.1
1941 Male, age 53, unknown 241.7
1851 Male, age 51, unknown 235.0
2241 Male, age 72, unknown 235.0
2409 Female, age 72, unknown 234.8
1916 Female, age 42, unknown 225.0
2583 Male, age 75, right hemisphere 222.3
2590 Female, age 75, unknown 212.1
2699 Male, age 18, unknown 205.1
2665 Male, age 74, both hemispheres 195.4
Superior colliculus
nTPM: 248.5
2261 Male, age 18, unknown 268.7
2087 Female, age 72, unknown 268.3
1796 Male, age 53, unknown 254.7
1913 Female, age 42, unknown 252.5
2668 Female, age 75, unknown 250.7
1995 Male, age 72, unknown 249.4
2664 Male, age 75, both hemispheres 244.8
2587 Male, age 74, left hemisphere 238.6
1895 Male, age 76, right hemisphere 230.8
1839 Male, age 51, unknown 226.4
Ventral tegmental area
nTPM: 228.6
2410 Female, age 72, unknown 254.4
2223 Female, age 72, unknown 238.1
2021 Male, age 53, unknown 223.0
1915 Female, age 42, unknown 222.6
2218 Male, age 76, both hemispheres 216.8
1942 Male, age 51, unknown 216.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 156.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 156.5
Samples: 139

Max nTPM: 346.8
Min nTPM: 68.1
Std nTPM: 45.3
Median nTPM: 148.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 346.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 315.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 273.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 272.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 258.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 250.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 239.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 235.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 229.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 228.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 219.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 219.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 216.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 213.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 205.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 204.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 203.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 203.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 199.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 199.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 196.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 195.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 194.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 193.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 193.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 193.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 190.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 190.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 189.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 189.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 188.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 187.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 187.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 184.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 183.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 181.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 181.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 179.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 177.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 177.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 175.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 173.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 172.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 171.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 167.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 167.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 166.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 165.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 164.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 163.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 162.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 162.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 161.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 161.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 160.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 158.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 157.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 156.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 156.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 156.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 154.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 154.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 152.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 151.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 151.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 150.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 148.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 148.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 148.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 148.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 147.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 147.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 145.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 145.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 145.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 145.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 145.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 144.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 143.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 143.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 143.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 142.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 142.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 142.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 142.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 141.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 141.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 141.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 141.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 137.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 137.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 137.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 137.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 135.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 135.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 134.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 134.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 133.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 133.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 132.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 131.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 129.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 128.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 127.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 127.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 126.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 126.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 125.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 125.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 124.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 122.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 121.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 121.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 120.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 115.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 113.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 112.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 111.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 108.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 107.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 107.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 107.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 106.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 106.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 105.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 104.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 101.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 101.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 100.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 100.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 98.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 95.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 94.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 93.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 90.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 90.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 86.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 73.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 68.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 666.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 666.0
FF:10158-103A5 76 years, female 666.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 19.4
Pig sample Sample description nTPM
Midbrain
nTPM: 19.4
Samples: 4

Max nTPM: 26.4
Min nTPM: 11.6
Sample A Female 19.9
Sample B Female 11.6
Sample C Male 26.4
Sample D Male 19.7
Periaqueductal gray
nTPM: 11.0
Samples: 3

Max nTPM: 13.6
Min nTPM: 9.4
Sample B Female 10.1
Sample C Male 13.6
Sample D Male 9.4
Substantia nigra
nTPM: 15.8
Samples: 4

Max nTPM: 20.1
Min nTPM: 12.3
Sample A Female 17.4
Sample B Female 13.2
Sample C Male 20.1
Sample D Male 12.3
Superior colliculi
nTPM: 18.0
Samples: 4

Max nTPM: 20.1
Min nTPM: 13.9
Sample A Female 19.1
Sample B Female 13.9
Sample C Male 19.0
Sample D Male 20.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 593.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 593.5
Samples: 4

Max nTPM: 622.2
Min nTPM: 580.1
Sample A Male 622.2
Sample B Male 585.2
Sample C Female 580.1
Sample D Female 586.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 13.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.6
1405 Antisense, RP_040324_01_A01, Mouse strain C57BL/6J (56 days, male) 13.6
1406 Antisense, RP_040324_01_A01, Mouse strain C57BL/6J (56 days, male) 9.1

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