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PTP4A2
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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:270.0 nTPM
HPA:270.0 nTPM
FANTOM5:278.1 Scaled Tags Per Million
Pig:197.9 nTPM
Mouse:91.3 nTPM
Allen mouse:0.7 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 270.0
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 242.0
2301 Female, age 85, both hemispheres 295.5
2188 Female, age 91, both hemispheres 270.1
2090 Male, age 80, both hemispheres 233.6
1984 Male, age 76, both hemispheres 168.7
Area postrema
nTPM: 257.2
2799 Male, age 61, both hemispheres 313.8
2306 Male, age 80, both hemispheres 256.4
2054 Male, age 76, both hemispheres 201.4
Cuneate nuclei
nTPM: 227.3
2381 Male, age 80, both hemispheres 250.8
2376 Male, age 61, both hemispheres 247.7
2131 Male, age 76, both hemispheres 183.4
Dorsal cochlear nucleus
nTPM: 249.8
2802 Male, age 74, right hemisphere 282.2
2378 Male, age 80, both hemispheres 258.2
2187 Female, age 91, both hemispheres 239.6
2370 Male, age 61, both hemispheres 237.0
2058 Male, age 76, both hemispheres 232.0
Dorsal medullary reticular nucleus
nTPM: 234.5
2373 Male, age 61, both hemispheres 244.0
2040 Female, age 85, both hemispheres 236.1
2088 Male, age 76, both hemispheres 223.5
Dorsal motor vagal complex
nTPM: 233.4
2797 Male, age 61, both hemispheres 347.6
2807 Female, age 85, both hemispheres 254.2
2185 Male, age 76, both hemispheres 250.9
2643 Male, age 74, both hemispheres 230.9
2133 Female, age 91, both hemispheres 210.5
2000 Male, age 74, unknown 201.3
2813 Female, age 72, unknown 195.4
2844 Male, age 55, unknown 176.4
Dorsal tegmental nucleus
nTPM: 233.7
2326 Male, age 74, both hemispheres 267.3
2083 Male, age 80, both hemispheres 237.3
1936 Male, age 76, left hemisphere 219.9
2358 Male, age 61, both hemispheres 210.3
Dorsolateral tegmental area
nTPM: 223.5
2654 Male, age 80, both hemispheres 254.2
2751 Female, age 85, both hemispheres 249.2
2337 Male, age 61, both hemispheres 228.3
2360 Male, age 74, both hemispheres 202.2
2141 Male, age 76, both hemispheres 183.5
Gigantocellular reticular nuclei, medullary
nTPM: 240.9
2387 Female, age 91, both hemispheres 287.4
2314 Male, age 61, both hemispheres 265.3
2310 Male, age 80, both hemispheres 242.1
1876 Female, age 85, both hemispheres 229.0
2022 Male, age 76, right hemisphere 228.2
2462 Male, age 74, both hemispheres 193.4
Gigantocellular reticular nuclei, pars
nTPM: 223.8
2330 Male, age 80, both hemispheres 245.0
2336 Male, age 61, both hemispheres 228.2
2084 Female, age 85, both hemispheres 227.2
2706 Male, age 80, both hemispheres 223.8
2168 Male, age 76, both hemispheres 194.7
Inferior olive
nTPM: 229.2
2379 Male, age 80, both hemispheres 248.0
2628 Female, age 91, both hemispheres 236.5
2085 Female, age 85, both hemispheres 232.3
2178 Male, age 61, both hemispheres 228.4
2563 Male, age 74, both hemispheres 200.6
Kolliker-Fuse nucleus
nTPM: 229.6
2793 Female, age 91, left hemisphere 257.7
2163 Male, age 80, both hemispheres 226.2
2315 Male, age 76, right hemisphere 204.9
Lateral lemniscal nuclei
nTPM: 230.9
2320 Female, age 91, left hemisphere 256.5
2036 Male, age 80, both hemispheres 245.2
2453 Male, age 74, right hemisphere 232.0
2169 Male, age 76, both hemispheres 217.4
2746 Female, age 85, left hemisphere 203.5
Lateral medullary reticular nucleus
nTPM: 223.6
2190 Female, age 85, both hemispheres 243.6
2374 Male, age 61, both hemispheres 233.2
2804 Female, age 91, both hemispheres 224.0
2044 Male, age 76, both hemispheres 222.4
2305 Male, age 74, both hemispheres 217.3
2852 Male, age 80, both hemispheres 201.3
Lateral parabrachial nucleus
nTPM: 238.4
2792 Male, age 76, both hemispheres 287.9
2013 Male, age 80, both hemispheres 246.4
2790 Male, age 61, both hemispheres 229.8
2139 Female, age 85, right hemisphere 189.4
Lateral vestibular nucleus
nTPM: 229.3
2311 Male, age 80, both hemispheres 242.8
2184 Male, age 76, both hemispheres 215.8
Locus coeruleus
nTPM: 189.3
2720 Male, age 74, both hemispheres 235.9
2162 Male, age 80, both hemispheres 211.2
2317 Female, age 72, unknown 183.3
2788 Male, age 74, unknown 183.2
2014 Male, age 55, unknown 181.6
1980 Male, age 76, both hemispheres 166.8
2123 Female, age 91, both hemispheres 163.0
Medial olivary nucleus
nTPM: 254.6
1943 Male, age 61, both hemispheres 267.4
1962 Male, age 76, both hemispheres 261.5
2138 Female, age 91, both hemispheres 247.5
2851 Male, age 80, both hemispheres 242.2
Medial parabrachial nucleus
nTPM: 224.2
2854 Male, age 80, both hemispheres 234.0
2170 Female, age 91, both hemispheres 232.5
2786 Male, age 76, both hemispheres 226.1
2156 Male, age 61, both hemispheres 223.5
2463 Female, age 85, right hemisphere 205.1
Medial periolivary nuclei
nTPM: 220.9
2458 Female, age 91, both hemispheres 259.1
2081 Male, age 80, both hemispheres 247.9
2063 Male, age 76, both hemispheres 213.0
2791 Male, age 74, right hemisphere 192.5
2171 Female, age 85, both hemispheres 192.2
Medial vestibular nucleus
nTPM: 207.0
2803 Female, age 91, both hemispheres 259.9
2093 Male, age 80, both hemispheres 226.1
2624 Male, age 61, both hemispheres 214.6
2801 Male, age 74, both hemispheres 190.6
2134 Male, age 76, both hemispheres 176.6
2743 Female, age 85, both hemispheres 174.1
Motor facial nucleus
nTPM: 228.3
2697 Female, age 85, both hemispheres 268.2
2327 Male, age 80, both hemispheres 243.4
2795 Female, age 91, both hemispheres 236.5
2126 Male, age 61, both hemispheres 219.1
2365 Male, age 74, right hemisphere 208.0
2062 Male, age 76, both hemispheres 194.7
Motor hypoglossal nucleus
nTPM: 223.6
2132 Female, age 85, both hemispheres 257.4
2182 Male, age 80, both hemispheres 241.3
2461 Male, age 61, both hemispheres 224.6
2125 Female, age 91, both hemispheres 220.6
2277 Male, age 76, both hemispheres 174.1
Motor trigeminal nucleus
nTPM: 229.2
2321 Female, age 91, both hemispheres 248.1
2309 Male, age 76, both hemispheres 236.1
2335 Male, age 61, both hemispheres 225.4
2560 Male, age 74, both hemispheres 223.5
2079 Male, age 80, both hemispheres 213.0
Nuclei of the trapezoid body
nTPM: 219.8
2368 Female, age 91, both hemispheres 246.0
2166 Male, age 80, both hemispheres 236.8
2159 Male, age 61, both hemispheres 220.4
1983 Male, age 76, both hemispheres 209.9
2735 Female, age 85, both hemispheres 186.0
Nucleus ambiguus
nTPM: 205.1
2071 Male, age 76, both hemispheres 251.5
2096 Female, age 85, both hemispheres 158.6
Nucleus cuneatus
nTPM: 249.4
2805 Female, age 91, both hemispheres 281.2
2380 Male, age 80, both hemispheres 280.4
2808 Female, age 85, both hemispheres 276.8
2562 Male, age 61, both hemispheres 228.6
2564 Male, age 74, both hemispheres 223.0
2100 Male, age 76, both hemispheres 206.1
Nucleus gracilis
nTPM: 262.5
2299 Female, age 85, both hemispheres 284.6
2382 Male, age 80, both hemispheres 278.7
2627 Male, age 74, both hemispheres 224.4
Nucleus raphe magnus
nTPM: 219.6
2459 Female, age 91, both hemispheres 259.9
2328 Male, age 80, both hemispheres 246.4
2051 Male, age 76, both hemispheres 239.3
2455 Male, age 74, both hemispheres 201.9
2160 Male, age 61, both hemispheres 185.6
2172 Female, age 85, both hemispheres 184.2
Nucleus raphe obscurus
nTPM: 251.4
2142 Male, age 76, midline 263.6
2845 Female, age 85, midline 258.4
2800 Male, age 61, midline 232.1
Nucleus raphe pallidus
nTPM: 235.3
2145 Male, age 76, midline 268.5
1924 Male, age 61, midline 227.1
2183 Male, age 80, midline 210.3
Nucleus tractus solitarii
nTPM: 184.3
2191 Female, age 85, both hemispheres 191.8
2656 Male, age 76, both hemispheres 185.3
2144 Female, age 91, right hemisphere 184.0
2307 Male, age 80, both hemispheres 176.0
Paramedian reticular nucleus
nTPM: 240.5
2052 Male, age 76, both hemispheres 287.2
2313 Male, age 61, both hemispheres 236.6
2057 Male, age 80, both hemispheres 222.1
2050 Female, age 85, both hemispheres 216.3
Parvicellular reticular nuclei
nTPM: 225.2
2095 Male, age 76, both hemispheres 239.5
2119 Male, age 80, both hemispheres 221.1
2558 Male, age 74, both hemispheres 215.1
Parvicellular reticular nuclei, medullary
nTPM: 218.8
2181 Male, age 80, left hemisphere 227.9
2189 Female, age 91, both hemispheres 223.7
2091 Female, age 85, both hemispheres 204.9
Peritrigeminal nucleus
nTPM: 209.8
2136 Male, age 76, both hemispheres 226.9
2179 Male, age 61, both hemispheres 213.0
2067 Female, age 85, both hemispheres 189.4
Pontine nuclei
nTPM: 230.2
2319 Female, age 91, both hemispheres 291.7
2454 Male, age 74, left hemisphere 264.8
2115 Male, age 80, left hemisphere 230.8
1968 Male, age 76, left hemisphere 228.0
1863 Male, age 55, unknown 222.9
2109 Female, age 72, unknown 219.4
2727 Male, age 61, right hemisphere 211.1
2787 Female, age 85, both hemispheres 173.4
Pontine raphe nucleus
nTPM: 210.8
2122 Female, age 85, midline 223.9
2853 Male, age 76, midline 197.8
Posteroventral cochlear nucleus
nTPM: 270.0
2135 Female, age 91, both hemispheres 308.8
2341 Male, age 80, both hemispheres 307.2
2371 Male, age 61, both hemispheres 283.1
2070 Male, age 76, both hemispheres 225.9
2752 Female, age 85, both hemispheres 225.0
Prepositus hypoglossal nucleus
nTPM: 199.5
2855 Female, age 85, right hemisphere 224.3
2086 Male, age 80, both hemispheres 174.6
Principal sensory trigeminal nucleus
nTPM: 215.8
2367 Female, age 91, left hemisphere 254.2
2324 Male, age 76, both hemispheres 224.7
2008 Male, age 80, left hemisphere 193.1
2158 Male, age 61, both hemispheres 191.0
Reticular pontine nucleus, caudal
nTPM: 245.9
2457 Female, age 91, both hemispheres 279.2
2559 Male, age 74, both hemispheres 248.1
2332 Male, age 80, right hemisphere 237.7
2092 Male, age 76, both hemispheres 218.6
Reticular pontine nucleus, oral
nTPM: 242.6
2366 Female, age 91, both hemispheres 301.8
1939 Male, age 80, both hemispheres 251.6
2167 Male, age 76, both hemispheres 236.1
2012 Female, age 85, both hemispheres 215.4
2361 Male, age 74, both hemispheres 208.0
Reticulotegmental nucleus
nTPM: 246.4
2452 Male, age 74, both hemispheres 270.1
2322 Female, age 91, both hemispheres 264.5
2333 Male, age 80, both hemispheres 245.8
2325 Male, age 76, both hemispheres 204.9
Spinal trigeminal nucleus, caudal
nTPM: 229.5
2312 Male, age 61, both hemispheres 260.0
2308 Male, age 80, both hemispheres 234.7
2390 Female, age 91, both hemispheres 225.6
2642 Male, age 74, both hemispheres 217.9
2447 Male, age 76, both hemispheres 209.3
Spinal trigeminal nucleus, interpolar
nTPM: 224.4
2389 Female, age 91, both hemispheres 248.2
2386 Female, age 85, both hemispheres 234.1
2033 Male, age 80, both hemispheres 229.5
2625 Male, age 61, both hemispheres 210.9
2066 Male, age 76, right hemisphere 199.2
Spinal trigeminal nucleus, oral
nTPM: 217.0
2164 Male, age 80, both hemispheres 237.4
1978 Male, age 76, both hemispheres 219.5
2737 Female, age 85, both hemispheres 194.1
Spinal vestibular nucleus
nTPM: 253.7
2384 Male, age 74, both hemispheres 309.0
2806 Female, age 85, both hemispheres 275.5
2796 Male, age 61, both hemispheres 247.0
2186 Female, age 91, both hemispheres 241.5
2748 Male, age 76, both hemispheres 228.3
2780 Male, age 80, both hemispheres 220.7
Subcoeruleus area
nTPM: 239.2
2369 Female, age 85, left hemisphere 274.9
2451 Male, age 74, both hemispheres 268.0
1958 Male, age 80, both hemispheres 224.8
2323 Female, age 91, left hemisphere 218.9
2089 Male, age 76, left hemisphere 209.4
Superior olive
nTPM: 229.3
2020 Male, age 76, both hemispheres 259.8
2329 Male, age 80, right hemisphere 242.5
2561 Female, age 91, both hemispheres 238.4
1875 Female, age 85, both hemispheres 205.8
2364 Male, age 74, right hemisphere 199.8
Superior vestibular nucleus
nTPM: 201.0
2015 Male, age 80, both hemispheres 218.5
2383 Male, age 74, both hemispheres 197.1
2061 Male, age 76, both hemispheres 187.4
Ventral medullary reticular nucleus
nTPM: 237.4
2372 Male, age 61, both hemispheres 258.8
2060 Male, age 76, both hemispheres 216.0
Ventral periolivary nuclei
nTPM: 219.4
2023 Male, age 76, both hemispheres 256.8
2794 Female, age 91, left hemisphere 223.1
2165 Male, age 80, both hemispheres 212.5
2130 Female, age 85, both hemispheres 185.3
Ventrolateral medulla, A1-C1 cell groups
nTPM: 223.8
2302 Female, age 91, both hemispheres 240.3
2118 Male, age 80, both hemispheres 238.5
2180 Male, age 61, both hemispheres 214.8
1986 Male, age 76, both hemispheres 214.4
2741 Female, age 85, both hemispheres 211.1
Ventrolateral tegmental area, A5 NE cell group
nTPM: 231.4
2456 Female, age 91, both hemispheres 255.8
2161 Male, age 80, both hemispheres 249.0
2840 Female, age 85, both hemispheres 238.1
1959 Male, age 76, both hemispheres 222.2
2359 Male, age 61, both hemispheres 216.7
2449 Male, age 74, both hemispheres 206.4

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 278.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 278.1
FF:10182-103D2 60 years, female 318.9
FF:10165-103B3 76 years, female 237.4
Medulla oblongata
Scaled Tags Per Million: 240.8
FF:10038-101F2 18-64 years, mixed 259.6
FF:10174-103C3 60 years, female 234.3
FF:10155-103A2 76 years, female 228.3
Pons
Scaled Tags Per Million: 278.1
FF:10033-101E6 18-54 years, mixed 278.1

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 197.9
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 186.4
Samples: 4

Max nTPM: 264.9
Min nTPM: 152.7
Sample A Female 264.9
Sample B Female 157.9
Sample C Male 170.2
Sample D Male 152.7
Pons
nTPM: 198.0
Samples: 4

Max nTPM: 219.1
Min nTPM: 172.2
Sample A Female 219.1
Sample B Female 172.2
Sample C Male 204.6
Sample D Male 195.9

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 91.3
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 91.3
Samples: 4

Max nTPM: 93.8
Min nTPM: 87.0
Sample A Male 87.0
Sample B Male 91.6
Sample C Female 92.8
Sample D Female 93.8

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 0.7
71280538 Antisense, RP_050818_01_A11, Mouse strain C57BL/6J (56 days, male) 1.4
77799059 Antisense, RP_070212_03_E04, Mouse strain C57BL/6J (56 days, male) 0.4
70813353 Antisense, RP_050712_03_G08, Mouse strain C57BL/6J (56 days, male) 0.3
Pons
Expression energy: 0.5
71280538 Antisense, RP_050818_01_A11, Mouse strain C57BL/6J (56 days, male) 0.9
77799059 Antisense, RP_070212_03_E04, Mouse strain C57BL/6J (56 days, male) 0.4
70813353 Antisense, RP_050712_03_G08, Mouse strain C57BL/6J (56 days, male) 0.2

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