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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:282.9 nTPM
HPA:282.9 nTPM
FANTOM5:1148.4 Scaled Tags Per Million
Pig:287.7 nTPM
Allen mouse:19.6 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 282.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 226.6
2188 Female, age 91, both hemispheres 264.6
2301 Female, age 85, both hemispheres 230.8
2090 Male, age 80, both hemispheres 217.9
1984 Male, age 76, both hemispheres 193.0
Dorsal cochlear nucleus
nTPM: 230.4
2802 Male, age 74, right hemisphere 282.7
2187 Female, age 91, both hemispheres 258.5
2378 Male, age 80, both hemispheres 215.0
2058 Male, age 76, both hemispheres 208.1
2370 Male, age 61, both hemispheres 187.5
Dorsal tegmental nucleus
nTPM: 213.7
2326 Male, age 74, both hemispheres 265.8
2083 Male, age 80, both hemispheres 222.2
1936 Male, age 76, left hemisphere 207.2
2358 Male, age 61, both hemispheres 159.7
Dorsolateral tegmental area
nTPM: 215.5
2751 Female, age 85, both hemispheres 258.4
2654 Male, age 80, both hemispheres 231.9
2360 Male, age 74, both hemispheres 228.2
2141 Male, age 76, both hemispheres 196.3
2337 Male, age 61, both hemispheres 162.8
Kolliker-Fuse nucleus
nTPM: 226.3
2793 Female, age 91, left hemisphere 230.2
2315 Male, age 76, right hemisphere 225.0
2163 Male, age 80, both hemispheres 223.8
Lateral lemniscal nuclei
nTPM: 247.3
2169 Male, age 76, both hemispheres 278.5
2036 Male, age 80, both hemispheres 269.9
2746 Female, age 85, left hemisphere 250.2
2453 Male, age 74, right hemisphere 222.1
2320 Female, age 91, left hemisphere 215.6
Lateral parabrachial nucleus
nTPM: 228.8
2139 Female, age 85, right hemisphere 254.0
2013 Male, age 80, both hemispheres 236.9
2792 Male, age 76, both hemispheres 231.2
2790 Male, age 61, both hemispheres 192.9
Lateral vestibular nucleus
nTPM: 211.1
2311 Male, age 80, both hemispheres 217.2
2184 Male, age 76, both hemispheres 205.0
Locus coeruleus
nTPM: 229.9
2014 Male, age 55, unknown 259.7
2788 Male, age 74, unknown 253.5
2720 Male, age 74, both hemispheres 234.8
2123 Female, age 91, both hemispheres 232.7
2317 Female, age 72, unknown 220.3
2162 Male, age 80, both hemispheres 209.5
1980 Male, age 76, both hemispheres 198.6
Medial olivary nucleus
nTPM: 240.4
2138 Female, age 91, both hemispheres 258.9
1943 Male, age 61, both hemispheres 248.0
1962 Male, age 76, both hemispheres 244.1
2851 Male, age 80, both hemispheres 210.6
Medial parabrachial nucleus
nTPM: 227.9
2170 Female, age 91, both hemispheres 285.1
2854 Male, age 80, both hemispheres 249.7
2463 Female, age 85, right hemisphere 213.7
2786 Male, age 76, both hemispheres 204.8
2156 Male, age 61, both hemispheres 186.5
Medial periolivary nuclei
nTPM: 260.5
2063 Male, age 76, both hemispheres 302.4
2791 Male, age 74, right hemisphere 282.3
2171 Female, age 85, both hemispheres 279.5
2081 Male, age 80, both hemispheres 225.8
2458 Female, age 91, both hemispheres 212.2
Motor facial nucleus
nTPM: 243.7
2062 Male, age 76, both hemispheres 304.0
2365 Male, age 74, right hemisphere 256.3
2697 Female, age 85, both hemispheres 233.4
2795 Female, age 91, both hemispheres 226.7
2126 Male, age 61, both hemispheres 226.3
2327 Male, age 80, both hemispheres 215.3
Motor trigeminal nucleus
nTPM: 213.1
2079 Male, age 80, both hemispheres 237.1
2560 Male, age 74, both hemispheres 218.9
2321 Female, age 91, both hemispheres 216.0
2309 Male, age 76, both hemispheres 212.3
2335 Male, age 61, both hemispheres 181.4
Nuclei of the trapezoid body
nTPM: 267.8
2159 Male, age 61, both hemispheres 315.3
1983 Male, age 76, both hemispheres 294.9
2735 Female, age 85, both hemispheres 277.7
2166 Male, age 80, both hemispheres 230.9
2368 Female, age 91, both hemispheres 220.5
Paramedian reticular nucleus
nTPM: 253.4
2050 Female, age 85, both hemispheres 274.9
2052 Male, age 76, both hemispheres 252.4
2057 Male, age 80, both hemispheres 243.6
2313 Male, age 61, both hemispheres 242.7
Pontine nuclei
nTPM: 282.9
2727 Male, age 61, right hemisphere 346.6
1863 Male, age 55, unknown 324.6
2109 Female, age 72, unknown 298.2
2454 Male, age 74, left hemisphere 294.7
2787 Female, age 85, both hemispheres 272.1
1968 Male, age 76, left hemisphere 264.3
2319 Female, age 91, both hemispheres 254.8
2115 Male, age 80, left hemisphere 207.7
Pontine raphe nucleus
nTPM: 247.0
2122 Female, age 85, midline 272.8
2853 Male, age 76, midline 221.3
Posteroventral cochlear nucleus
nTPM: 235.0
2135 Female, age 91, both hemispheres 281.1
2341 Male, age 80, both hemispheres 247.1
2752 Female, age 85, both hemispheres 241.5
2070 Male, age 76, both hemispheres 210.8
2371 Male, age 61, both hemispheres 194.4
Principal sensory trigeminal nucleus
nTPM: 244.8
2158 Male, age 61, both hemispheres 274.7
2008 Male, age 80, left hemisphere 271.7
2367 Female, age 91, left hemisphere 234.9
2324 Male, age 76, both hemispheres 197.9
Reticular pontine nucleus, caudal
nTPM: 237.6
2092 Male, age 76, both hemispheres 254.2
2559 Male, age 74, both hemispheres 253.9
2457 Female, age 91, both hemispheres 232.3
2332 Male, age 80, right hemisphere 210.0
Reticular pontine nucleus, oral
nTPM: 246.7
2361 Male, age 74, both hemispheres 276.8
2012 Female, age 85, both hemispheres 264.6
1939 Male, age 80, both hemispheres 240.1
2366 Female, age 91, both hemispheres 235.1
2167 Male, age 76, both hemispheres 217.0
Reticulotegmental nucleus
nTPM: 226.1
2325 Male, age 76, both hemispheres 241.4
2322 Female, age 91, both hemispheres 231.4
2452 Male, age 74, both hemispheres 221.9
2333 Male, age 80, both hemispheres 209.7
Spinal trigeminal nucleus, oral
nTPM: 209.4
2737 Female, age 85, both hemispheres 216.2
2164 Male, age 80, both hemispheres 206.3
1978 Male, age 76, both hemispheres 205.7
Subcoeruleus area
nTPM: 238.5
2369 Female, age 85, left hemisphere 257.5
1958 Male, age 80, both hemispheres 255.3
2089 Male, age 76, left hemisphere 238.0
2451 Male, age 74, both hemispheres 226.3
2323 Female, age 91, left hemisphere 215.4
Superior olive
nTPM: 252.7
1875 Female, age 85, both hemispheres 296.1
2020 Male, age 76, both hemispheres 272.8
2364 Male, age 74, right hemisphere 271.3
2329 Male, age 80, right hemisphere 218.4
2561 Female, age 91, both hemispheres 204.9
Superior vestibular nucleus
nTPM: 234.9
2383 Male, age 74, both hemispheres 267.1
2015 Male, age 80, both hemispheres 241.7
2061 Male, age 76, both hemispheres 195.9
Ventral periolivary nuclei
nTPM: 250.8
2023 Male, age 76, both hemispheres 280.7
2130 Female, age 85, both hemispheres 257.7
2165 Male, age 80, both hemispheres 254.2
2794 Female, age 91, left hemisphere 210.5
Ventrolateral tegmental area, A5 NE cell group
nTPM: 229.2
1959 Male, age 76, both hemispheres 257.4
2840 Female, age 85, both hemispheres 242.5
2449 Male, age 74, both hemispheres 234.0
2161 Male, age 80, both hemispheres 230.5
2456 Female, age 91, both hemispheres 217.9
2359 Male, age 61, both hemispheres 192.9

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1148.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 631.6
FF:10165-103B3 76 years, female 641.4
FF:10182-103D2 60 years, female 621.8
Pons
Scaled Tags Per Million: 1148.4
FF:10033-101E6 18-54 years, mixed 1148.4

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 287.7
Pig sample Sample description nTPM
Pons
nTPM: 287.7
Samples: 4

Max nTPM: 349.5
Min nTPM: 224.6
Sample A Female 274.1
Sample B Female 224.6
Sample C Male 349.5
Sample D Male 302.4

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 19.6
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 19.6
67752306 Antisense, RP_040922_01_D04, Mouse strain C57BL/6J (56 days, male) 21.9
77413696 Antisense, RP_070205_01_D08, Mouse strain C57BL/6J (56 days, male) 17.4
77620375 Antisense, RP_070205_01_D08, Mouse strain C57BL/6J (56 days, male) 16.5
68196968 Antisense, RP_040922_01_D04, Mouse strain C57BL/6J (56 days, male) 14.9

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.