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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:457.1 nTPM
HPA:457.1 nTPM
GTEx:715.4 nTPM
FANTOM5:651.6 Scaled Tags Per Million
Pig:348.1 nTPM
Mouse:572.2 nTPM
Allen mouse:14.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 457.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 415.4
2019 Male, age 18, unknown 446.4
1870 Female, age 42, unknown 444.7
2411 Female, age 72, unknown 437.2
1827 Male, age 72, unknown 434.7
2828 Female, age 72, unknown 413.4
1833 Male, age 53, unknown 413.0
2219 Male, age 76, both hemispheres 410.8
1830 Male, age 51, unknown 410.5
2666 Male, age 74, left hemisphere 378.9
2586 Male, age 75, left hemisphere 365.0
Dorsal raphe nucleus
nTPM: 444.3
2298 Female, age 72, unknown 479.4
1828 Male, age 53, unknown 443.0
2750 Male, age 76, both hemispheres 442.0
2047 Male, age 72, unknown 436.3
2016 Female, age 72, unknown 420.7
Inferior colliculus
nTPM: 434.2
2097 Female, age 72, unknown 465.9
1890 Male, age 53, unknown 430.7
1848 Female, age 42, unknown 421.0
2849 Male, age 72, unknown 419.3
Median raphe nucleus
nTPM: 449.2
2220 Male, age 76, midline 449.2
Pedunculopontine tegmental nucleus
nTPM: 457.1
2334 Male, age 80, both hemispheres 466.2
1921 Female, age 85, both hemispheres 454.6
2338 Male, age 61, both hemispheres 450.4
Periaquaductal grey, anterior
nTPM: 432.7
1947 Male, age 18, unknown 442.5
2502 Female, age 75, unknown 440.4
1795 Male, age 51, unknown 415.2
Periaquaductal grey, dorsal
nTPM: 425.5
2850 Male, age 76, both hemispheres 456.3
1840 Male, age 53, unknown 429.7
1831 Male, age 72, unknown 414.6
2464 Female, age 72, unknown 401.3
Periaquaductal grey, lateral
nTPM: 429.5
2272 Male, age 74, both hemispheres 447.7
2140 Male, age 76, both hemispheres 427.5
2053 Male, age 18, unknown 413.4
Pretectal area
nTPM: 455.6
1944 Female, age 72, unknown 485.7
2273 Male, age 74, both hemispheres 481.6
1817 Female, age 42, unknown 477.3
2667 Female, age 75, unknown 475.0
1816 Male, age 51, unknown 474.5
2224 Female, age 72, unknown 463.4
2007 Male, age 72, unknown 459.2
1815 Male, age 53, unknown 452.5
2825 Male, age 18, unknown 422.7
2316 Male, age 76, right hemisphere 412.3
2407 Male, age 75, both hemispheres 407.6
Red nucleus
nTPM: 428.7
1821 Female, age 72, unknown 466.5
2725 Female, age 75, unknown 456.3
1954 Female, age 42, unknown 443.0
2823 Male, age 76, right hemisphere 436.8
2503 Female, age 72, unknown 436.1
2785 Male, age 18, unknown 435.0
1865 Male, age 51, unknown 431.8
1904 Male, age 53, unknown 425.5
2227 Male, age 72, unknown 418.0
2769 Male, age 72, unknown 415.1
2588 Male, age 74, left hemisphere 394.5
2584 Male, age 75, left hemisphere 385.7
Substantia nigra
nTPM: 451.0
2241 Male, age 72, unknown 512.9
1889 Female, age 72, unknown 480.1
1916 Female, age 42, unknown 478.3
2409 Female, age 72, unknown 464.5
1851 Male, age 51, unknown 461.6
1941 Male, age 53, unknown 452.4
2699 Male, age 18, unknown 435.6
2665 Male, age 74, both hemispheres 415.6
2590 Female, age 75, unknown 413.6
2583 Male, age 75, right hemisphere 395.3
Superior colliculus
nTPM: 428.5
2587 Male, age 74, left hemisphere 469.3
2087 Female, age 72, unknown 454.2
1796 Male, age 53, unknown 442.7
2261 Male, age 18, unknown 433.3
1913 Female, age 42, unknown 430.9
1895 Male, age 76, right hemisphere 430.3
1839 Male, age 51, unknown 420.4
2668 Female, age 75, unknown 409.5
1995 Male, age 72, unknown 404.7
2664 Male, age 75, both hemispheres 389.5
Ventral tegmental area
nTPM: 447.9
1915 Female, age 42, unknown 466.7
2410 Female, age 72, unknown 454.4
2218 Male, age 76, both hemispheres 454.2
2223 Female, age 72, unknown 444.9
1942 Male, age 51, unknown 440.1
2021 Male, age 53, unknown 427.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 715.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 715.4
Samples: 139

Max nTPM: 1113.2
Min nTPM: 435.8
Std nTPM: 133.9
Median nTPM: 690.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1113.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1064.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1037.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 998.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 980.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 968.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 955.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 953.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 945.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 920.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 908.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 902.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 889.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 875.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 874.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 869.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 869.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 867.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 866.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 857.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 854.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 852.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 851.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 851.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 848.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 847.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 847.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 846.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 844.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 844.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 842.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 834.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 830.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 830.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 827.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 826.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 826.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 824.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 819.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 816.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 800.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 794.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 773.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 768.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 765.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 763.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 761.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 759.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 757.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 754.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 754.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 753.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 751.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 743.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 736.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 735.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 723.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 720.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 720.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 712.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 710.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 709.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 707.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 705.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 703.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 698.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 696.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 694.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 693.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 690.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 689.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 689.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 687.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 680.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 679.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 679.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 679.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 677.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 676.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 675.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 673.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 669.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 666.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 666.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 662.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 661.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 660.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 657.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 657.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 657.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 655.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 648.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 647.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 645.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 644.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 643.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 636.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 633.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 632.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 629.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 627.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 622.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 618.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 617.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 616.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 610.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 609.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 607.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 607.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 604.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 604.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 603.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 598.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 596.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 593.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 591.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 583.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 578.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 574.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 571.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 570.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 569.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 566.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 565.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 553.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 552.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 552.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 547.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 547.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 546.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 536.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 526.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 517.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 508.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 503.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 474.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 469.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 448.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 435.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 651.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 651.6
FF:10158-103A5 76 years, female 651.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 348.1
Pig sample Sample description nTPM
Midbrain
nTPM: 348.1
Samples: 4

Max nTPM: 435.1
Min nTPM: 298.1
Sample A Female 435.1
Sample B Female 319.3
Sample C Male 339.9
Sample D Male 298.1
Periaqueductal gray
nTPM: 254.2
Samples: 3

Max nTPM: 262.3
Min nTPM: 243.8
Sample B Female 256.5
Sample C Male 262.3
Sample D Male 243.8
Substantia nigra
nTPM: 294.9
Samples: 4

Max nTPM: 380.4
Min nTPM: 253.0
Sample A Female 380.4
Sample B Female 255.1
Sample C Male 291.0
Sample D Male 253.0
Superior colliculi
nTPM: 321.0
Samples: 4

Max nTPM: 360.5
Min nTPM: 248.9
Sample A Female 360.5
Sample B Female 248.9
Sample C Male 357.2
Sample D Male 317.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 572.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 572.2
Samples: 4

Max nTPM: 578.2
Min nTPM: 558.9
Sample A Male 573.7
Sample B Male 578.2
Sample C Female 577.9
Sample D Female 558.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.4
73573175 Antisense, RP_051121_03_D09, Mouse strain C57BL/6J (56 days, male) 14.4

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