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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:1025.1 nTPM
HPA:1025.1 nTPM
GTEx:1352.7 nTPM
FANTOM5:22.7 Scaled Tags Per Million
Pig:84.0 nTPM
Mouse:785.1 nTPM
Allen mouse:15.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 1025.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1002.5
2666 Male, age 74, left hemisphere 1020.3
2411 Female, age 72, unknown 1018.9
1870 Female, age 42, unknown 1017.0
1827 Male, age 72, unknown 1003.3
2828 Female, age 72, unknown 1001.6
1830 Male, age 51, unknown 1000.2
2219 Male, age 76, both hemispheres 994.5
1833 Male, age 53, unknown 991.3
2586 Male, age 75, left hemisphere 989.8
2019 Male, age 18, unknown 987.9
Dorsal raphe nucleus
nTPM: 1009.8
2298 Female, age 72, unknown 1046.7
2016 Female, age 72, unknown 1025.2
2750 Male, age 76, both hemispheres 1002.8
1828 Male, age 53, unknown 996.1
2047 Male, age 72, unknown 978.1
Inferior colliculus
nTPM: 1012.0
1890 Male, age 53, unknown 1024.2
2097 Female, age 72, unknown 1021.2
2849 Male, age 72, unknown 1001.9
1848 Female, age 42, unknown 1000.7
Median raphe nucleus
nTPM: 995.2
2220 Male, age 76, midline 995.2
Pedunculopontine tegmental nucleus
nTPM: 1014.4
2338 Male, age 61, both hemispheres 1030.9
2334 Male, age 80, both hemispheres 1026.5
1921 Female, age 85, both hemispheres 986.0
Periaquaductal grey, anterior
nTPM: 1014.6
2502 Female, age 75, unknown 1043.2
1947 Male, age 18, unknown 1005.6
1795 Male, age 51, unknown 994.9
Periaquaductal grey, dorsal
nTPM: 1011.2
1840 Male, age 53, unknown 1040.7
2464 Female, age 72, unknown 1009.2
1831 Male, age 72, unknown 1002.9
2850 Male, age 76, both hemispheres 992.1
Periaquaductal grey, lateral
nTPM: 997.4
2053 Male, age 18, unknown 1003.3
2140 Male, age 76, both hemispheres 1001.1
2272 Male, age 74, both hemispheres 987.6
Pretectal area
nTPM: 997.6
2224 Female, age 72, unknown 1018.9
2316 Male, age 76, right hemisphere 1017.5
2825 Male, age 18, unknown 1015.1
2273 Male, age 74, both hemispheres 1003.7
1815 Male, age 53, unknown 1001.3
1816 Male, age 51, unknown 991.3
2007 Male, age 72, unknown 991.2
1817 Female, age 42, unknown 988.7
1944 Female, age 72, unknown 984.1
2667 Female, age 75, unknown 982.1
2407 Male, age 75, both hemispheres 979.7
Red nucleus
nTPM: 1016.6
2503 Female, age 72, unknown 1065.3
1865 Male, age 51, unknown 1031.5
1821 Female, age 72, unknown 1026.8
2725 Female, age 75, unknown 1023.3
1904 Male, age 53, unknown 1019.5
2227 Male, age 72, unknown 1018.8
2769 Male, age 72, unknown 1012.1
2588 Male, age 74, left hemisphere 1010.1
1954 Female, age 42, unknown 1008.6
2584 Male, age 75, left hemisphere 1001.8
2785 Male, age 18, unknown 997.9
2823 Male, age 76, right hemisphere 983.5
Substantia nigra
nTPM: 1025.1
2241 Male, age 72, unknown 1077.1
1851 Male, age 51, unknown 1053.1
2665 Male, age 74, both hemispheres 1044.4
2699 Male, age 18, unknown 1043.5
2409 Female, age 72, unknown 1029.3
1916 Female, age 42, unknown 1018.4
2590 Female, age 75, unknown 1015.2
1889 Female, age 72, unknown 996.6
1941 Male, age 53, unknown 991.5
2583 Male, age 75, right hemisphere 982.1
Superior colliculus
nTPM: 1008.1
2587 Male, age 74, left hemisphere 1035.0
1913 Female, age 42, unknown 1025.5
1995 Male, age 72, unknown 1020.8
1796 Male, age 53, unknown 1012.1
2261 Male, age 18, unknown 1005.5
1839 Male, age 51, unknown 1001.8
2668 Female, age 75, unknown 998.0
1895 Male, age 76, right hemisphere 997.9
2087 Female, age 72, unknown 992.6
2664 Male, age 75, both hemispheres 991.6
Ventral tegmental area
nTPM: 1021.0
1915 Female, age 42, unknown 1042.6
2223 Female, age 72, unknown 1032.0
2021 Male, age 53, unknown 1023.6
2410 Female, age 72, unknown 1020.8
1942 Male, age 51, unknown 1012.6
2218 Male, age 76, both hemispheres 994.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1352.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1352.7
Samples: 139

Max nTPM: 4076.3
Min nTPM: 526.0
Std nTPM: 556.7
Median nTPM: 1233.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4076.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3588.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3339.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2869.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2775.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2463.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2423.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2344.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2216.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2172.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2165.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2098.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2095.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1995.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1979.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1893.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1863.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1859.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1858.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1851.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1812.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1808.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1730.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1730.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1716.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1697.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1693.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1683.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1675.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1640.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1639.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1618.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1599.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1572.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1559.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1534.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1526.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1515.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1492.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1480.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1456.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1451.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1442.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1429.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1420.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1418.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1414.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1411.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1411.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1385.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1380.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1378.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1375.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1361.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1352.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1340.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1337.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1322.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1305.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1303.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1290.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1280.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1280.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1280.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1275.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1273.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1262.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1247.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1246.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1233.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1228.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1218.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1209.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1197.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1196.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1179.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1166.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1162.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1160.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1155.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1150.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1132.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1130.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1122.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1118.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1107.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1098.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1089.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1087.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1087.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1086.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1062.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1062.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1057.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1055.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1050.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1048.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1048.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1034.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1027.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1021.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1018.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1017.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1007.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 996.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 995.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 972.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 969.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 956.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 947.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 939.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 936.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 932.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 926.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 920.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 883.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 879.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 878.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 843.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 843.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 842.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 835.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 833.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 827.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 822.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 819.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 818.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 811.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 804.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 803.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 787.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 783.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 773.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 732.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 720.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 718.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 702.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 614.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 526.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 22.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 22.7
FF:10158-103A5 76 years, female 22.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 84.0
Pig sample Sample description nTPM
Midbrain
nTPM: 75.1
Samples: 4

Max nTPM: 96.2
Min nTPM: 59.5
Sample A Female 96.2
Sample B Female 83.6
Sample C Male 61.2
Sample D Male 59.5
Periaqueductal gray
nTPM: 65.9
Samples: 3

Max nTPM: 68.9
Min nTPM: 61.2
Sample B Female 67.5
Sample C Male 68.9
Sample D Male 61.2
Substantia nigra
nTPM: 78.4
Samples: 4

Max nTPM: 104.9
Min nTPM: 58.7
Sample A Female 104.9
Sample B Female 87.9
Sample C Male 62.1
Sample D Male 58.7
Superior colliculi
nTPM: 84.0
Samples: 4

Max nTPM: 97.8
Min nTPM: 67.9
Sample A Female 96.1
Sample B Female 97.8
Sample C Male 74.3
Sample D Male 67.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 785.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 785.1
Samples: 4

Max nTPM: 839.7
Min nTPM: 736.1
Sample A Male 839.7
Sample B Male 792.3
Sample C Female 736.1
Sample D Female 772.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.2
68191186 Antisense, RP_041122_02_H09, Mouse strain C57BL/6J (56 days, male) 15.2

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