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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 217.6
Min nTPM: 50.9
Std nTPM: 28.2
Median nTPM:
413_1
59 years, female
217.6
501_1
88 years, male
204.1
491_1
89 years, female
174.0
414_1
84 years, female
162.0
265_1
87 years, male
143.1
316_1
62 years, male
137.3
375_1
74 years, female
133.1
142_1
61 years, female
132.5
396_1
62 years, male
128.0
119_1
70 years, female
127.0
42_1
85 years, male
126.2
120_1
70 years, female
124.5
452_1
88 years, female
123.3
41_1
94 years, female
123.0
506_1
65 years, male
121.3
313_1
79 years, female
119.3
4_1
88 years, female
118.6
384_1
83 years, male
117.8
149_1
88 years, male
117.2
237_1
82 years, male
115.0
466_1
57 years, female
114.7
264_1
73 years, female
112.3
324_1
76 years, male
110.9
145_1
84 years, male
109.6
308_1
70 years, female
109.4
286_1
68 years, female
108.0
490_1
67 years, female
107.6
526_1
61 years, male
107.3
81_1
67 years, male
107.2
17_1
71 years, male
105.9
480_1
63 years, male
105.2
153_1
70 years, female
104.4
499_1
55 years, female
104.4
379_1
60 years, male
103.3
447_1
81 years, male
103.1
139_1
64 years, female
103.0
162_1
79 years, female
102.7
117_1
61 years, male
100.7
173_1
67 years, male
100.2
35_1
74 years, female
99.2
229_1
69 years, female
98.6
288_1
66 years, female
98.5
89_1
63 years, male
97.9
9_1
66 years, female
97.0
217_1
76 years, male
96.5
2_1
77 years, female
96.1
348_1
84 years, male
95.1
254_1
77 years, female
94.6
315_1
62 years, female
94.0
43_1
64 years, female
93.8
350_1
84 years, female
93.6
355_1
70 years, female
92.0
295_1
61 years, female
91.1
314_1
67 years, male
89.7
311_1
78 years, male
89.1
291_1
76 years, male
89.0
126_1
63 years, male
88.8
99_1
64 years, male
88.7
109_1
81 years, female
88.6
321_1
62 years, female
88.1
376_1
75 years, female
88.1
518_1
75 years, female
85.2
189_1
76 years, male
83.6
115_1
83 years, male
83.5
377_1
82 years, female
83.0
389_1
86 years, female
82.8
495_1
57 years, female
82.6
353_1
82 years, female
81.8
137_1
83 years, male
80.4
349_1
83 years, male
79.6
172_1
72 years, female
79.5
415_1
77 years, female
78.5
292_1
71 years, male
78.4
394_1
75 years, female
78.3
307_1
66 years, female
77.4
468_1
89 years, male
77.4
354_1
81 years, female
77.2
322_1
76 years, male
77.0
425_1
59 years, female
76.9
6_1
73 years, female
76.6
177_1
74 years, male
76.0
405_1
91 years, male
75.2
18_1
88 years, male
74.6
406_1
79 years, male
73.9
404_1
82 years, female
73.8
32_1
67 years, male
73.7
347_1
72 years, male
72.4
351_1
91 years, male
70.7
320_1
89 years, female
70.0
266_1
85 years, male
69.6
352_1
62 years, male
69.4
517_1
88 years, male
68.2
386_1
76 years, male
68.1
319_1
81 years, male
67.3
356_1
87 years, female
67.3
163_1
78 years, male
66.5
318_1
68 years, male
63.0
251_1
78 years, male
60.7
317_1
60 years, male
60.4
243_1
75 years, male
57.1
218_1
71 years, female
56.1
335_1
73 years, female
55.3
503_1
68 years, male
51.6
246_1
77 years, male
51.1
293_1
68 years, female
50.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
