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S100A1
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  • S100A1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:894.8 nTPM
HPA:894.8 nTPM
GTEx:1164.0 nTPM
FANTOM5:785.3 Scaled Tags Per Million
Pig:3080.7 nTPM
Mouse:224.0 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 894.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 837.4
2828 Female, age 72, unknown 891.2
1833 Male, age 53, unknown 863.9
1870 Female, age 42, unknown 863.2
2586 Male, age 75, left hemisphere 846.0
2411 Female, age 72, unknown 839.1
1830 Male, age 51, unknown 831.2
1827 Male, age 72, unknown 815.5
2019 Male, age 18, unknown 811.6
2666 Male, age 74, left hemisphere 809.2
2219 Male, age 76, both hemispheres 802.9
Dorsal raphe nucleus
nTPM: 803.5
2750 Male, age 76, both hemispheres 863.8
1828 Male, age 53, unknown 803.6
2016 Female, age 72, unknown 790.5
2298 Female, age 72, unknown 785.2
2047 Male, age 72, unknown 774.1
Inferior colliculus
nTPM: 796.4
2849 Male, age 72, unknown 825.9
1848 Female, age 42, unknown 824.9
1890 Male, age 53, unknown 784.8
2097 Female, age 72, unknown 750.0
Median raphe nucleus
nTPM: 811.6
2220 Male, age 76, midline 811.6
Pedunculopontine tegmental nucleus
nTPM: 809.8
2334 Male, age 80, both hemispheres 862.1
1921 Female, age 85, both hemispheres 788.2
2338 Male, age 61, both hemispheres 779.2
Periaquaductal grey, anterior
nTPM: 776.8
1795 Male, age 51, unknown 788.1
1947 Male, age 18, unknown 771.7
2502 Female, age 75, unknown 770.6
Periaquaductal grey, dorsal
nTPM: 788.8
2850 Male, age 76, both hemispheres 811.7
2464 Female, age 72, unknown 797.7
1831 Male, age 72, unknown 777.7
1840 Male, age 53, unknown 767.9
Periaquaductal grey, lateral
nTPM: 805.2
2053 Male, age 18, unknown 831.8
2140 Male, age 76, both hemispheres 812.5
2272 Male, age 74, both hemispheres 771.3
Pretectal area
nTPM: 808.8
2667 Female, age 75, unknown 874.7
1815 Male, age 53, unknown 851.6
1817 Female, age 42, unknown 846.4
2316 Male, age 76, right hemisphere 834.8
2825 Male, age 18, unknown 826.5
2224 Female, age 72, unknown 807.9
1944 Female, age 72, unknown 794.9
1816 Male, age 51, unknown 784.9
2007 Male, age 72, unknown 776.2
2273 Male, age 74, both hemispheres 766.5
2407 Male, age 75, both hemispheres 732.3
Red nucleus
nTPM: 894.8
2227 Male, age 72, unknown 962.7
2769 Male, age 72, unknown 948.2
1954 Female, age 42, unknown 941.4
2503 Female, age 72, unknown 940.5
1821 Female, age 72, unknown 938.7
1904 Male, age 53, unknown 919.6
2823 Male, age 76, right hemisphere 917.2
1865 Male, age 51, unknown 899.5
2588 Male, age 74, left hemisphere 857.2
2725 Female, age 75, unknown 826.0
2785 Male, age 18, unknown 807.8
2584 Male, age 75, left hemisphere 778.7
Substantia nigra
nTPM: 814.6
2699 Male, age 18, unknown 919.5
1916 Female, age 42, unknown 868.3
1851 Male, age 51, unknown 834.8
2665 Male, age 74, both hemispheres 816.7
1889 Female, age 72, unknown 815.0
2590 Female, age 75, unknown 793.0
2583 Male, age 75, right hemisphere 786.9
2409 Female, age 72, unknown 782.3
1941 Male, age 53, unknown 775.1
2241 Male, age 72, unknown 754.9
Superior colliculus
nTPM: 805.8
1913 Female, age 42, unknown 852.6
1995 Male, age 72, unknown 844.2
1796 Male, age 53, unknown 817.7
1839 Male, age 51, unknown 817.7
2668 Female, age 75, unknown 816.4
2587 Male, age 74, left hemisphere 812.4
2087 Female, age 72, unknown 789.8
1895 Male, age 76, right hemisphere 775.4
2261 Male, age 18, unknown 768.4
2664 Male, age 75, both hemispheres 763.1
Ventral tegmental area
nTPM: 831.0
2223 Female, age 72, unknown 926.2
2218 Male, age 76, both hemispheres 836.4
2410 Female, age 72, unknown 823.3
1915 Female, age 42, unknown 814.4
2021 Male, age 53, unknown 793.4
1942 Male, age 51, unknown 792.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1164.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1164.0
Samples: 139

Max nTPM: 3039.0
Min nTPM: 188.5
Std nTPM: 472.6
Median nTPM: 1118.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3039.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2471.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2368.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2225.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2189.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 2098.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2083.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1995.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1994.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1957.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1910.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1909.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1861.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1851.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1767.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1752.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1752.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1708.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1674.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1639.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1629.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1594.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1569.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1568.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1540.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1522.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1506.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1498.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1495.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1489.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1438.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1424.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1422.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1408.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1395.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1393.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1392.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1386.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1375.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1360.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1351.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1350.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1347.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1343.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1340.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1335.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1312.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1297.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1286.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1268.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1268.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1256.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1245.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1240.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1238.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1228.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1204.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1197.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1195.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1193.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1188.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1186.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1180.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1171.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1148.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1147.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1141.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1126.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1121.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1118.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1109.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1099.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1092.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1084.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1083.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1070.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1069.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1042.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1035.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1034.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1023.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1017.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1010.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1000.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 983.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 972.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 971.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 967.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 964.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 957.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 953.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 948.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 946.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 918.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 912.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 909.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 904.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 873.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 870.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 852.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 850.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 846.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 839.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 820.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 780.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 776.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 764.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 761.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 759.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 758.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 755.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 754.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 752.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 749.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 749.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 745.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 726.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 718.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 705.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 698.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 678.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 673.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 669.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 666.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 666.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 641.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 614.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 613.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 575.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 561.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 546.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 506.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 492.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 478.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 471.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 426.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 402.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 238.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 188.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 785.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 785.3
FF:10158-103A5 76 years, female 785.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 3080.7
Pig sample Sample description nTPM
Midbrain
nTPM: 3050.8
Samples: 4

Max nTPM: 5611.3
Min nTPM: 1432.2
Sample A Female 5611.3
Sample B Female 3210.3
Sample C Male 1949.3
Sample D Male 1432.2
Periaqueductal gray
nTPM: 2739.8
Samples: 3

Max nTPM: 3107.3
Min nTPM: 2365.0
Sample B Female 3107.3
Sample C Male 2747.2
Sample D Male 2365.0
Substantia nigra
nTPM: 3080.7
Samples: 4

Max nTPM: 4051.0
Min nTPM: 2486.9
Sample A Female 4051.0
Sample B Female 2486.9
Sample C Male 2809.2
Sample D Male 2975.8
Superior colliculi
nTPM: 2165.6
Samples: 4

Max nTPM: 2805.7
Min nTPM: 1161.2
Sample A Female 2805.7
Sample B Female 1161.2
Sample C Male 2184.0
Sample D Male 2511.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 224.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 224.0
Samples: 4

Max nTPM: 235.5
Min nTPM: 217.2
Sample A Male 235.5
Sample B Male 217.2
Sample C Female 217.2
Sample D Female 226.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
70429411 Antisense, RP_050614_01_F03, Mouse strain C57BL/6J (56 days, male) 0.5

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