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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:538.3 nTPM
HPA:538.3 nTPM
GTEx:517.1 nTPM
FANTOM5:238.8 Scaled Tags Per Million
Pig:163.9 nTPM
Mouse:441.2 nTPM
Allen mouse:0.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 538.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 521.1
1870 Female, age 42, unknown 533.5
2666 Male, age 74, left hemisphere 529.4
1827 Male, age 72, unknown 528.4
2828 Female, age 72, unknown 525.9
2019 Male, age 18, unknown 525.0
2219 Male, age 76, both hemispheres 521.0
1833 Male, age 53, unknown 519.3
1830 Male, age 51, unknown 512.7
2411 Female, age 72, unknown 510.9
2586 Male, age 75, left hemisphere 504.9
Dorsal raphe nucleus
nTPM: 518.6
1828 Male, age 53, unknown 525.7
2047 Male, age 72, unknown 522.0
2750 Male, age 76, both hemispheres 519.7
2298 Female, age 72, unknown 516.4
2016 Female, age 72, unknown 509.0
Inferior colliculus
nTPM: 523.2
1890 Male, age 53, unknown 529.2
2849 Male, age 72, unknown 522.5
1848 Female, age 42, unknown 521.1
2097 Female, age 72, unknown 520.0
Median raphe nucleus
nTPM: 538.3
2220 Male, age 76, midline 538.3
Pedunculopontine tegmental nucleus
nTPM: 535.6
2338 Male, age 61, both hemispheres 543.1
2334 Male, age 80, both hemispheres 536.0
1921 Female, age 85, both hemispheres 527.9
Periaquaductal grey, anterior
nTPM: 520.7
1795 Male, age 51, unknown 524.2
1947 Male, age 18, unknown 520.6
2502 Female, age 75, unknown 517.3
Periaquaductal grey, dorsal
nTPM: 515.1
2850 Male, age 76, both hemispheres 527.8
1840 Male, age 53, unknown 516.9
1831 Male, age 72, unknown 513.7
2464 Female, age 72, unknown 502.1
Periaquaductal grey, lateral
nTPM: 512.3
2140 Male, age 76, both hemispheres 515.8
2053 Male, age 18, unknown 512.4
2272 Male, age 74, both hemispheres 508.7
Pretectal area
nTPM: 531.2
1944 Female, age 72, unknown 557.2
2007 Male, age 72, unknown 547.3
1817 Female, age 42, unknown 546.7
1816 Male, age 51, unknown 542.5
2667 Female, age 75, unknown 534.9
1815 Male, age 53, unknown 531.7
2407 Male, age 75, both hemispheres 524.5
2825 Male, age 18, unknown 517.6
2224 Female, age 72, unknown 517.5
2273 Male, age 74, both hemispheres 511.7
2316 Male, age 76, right hemisphere 511.3
Red nucleus
nTPM: 522.0
2785 Male, age 18, unknown 534.9
2725 Female, age 75, unknown 533.4
2584 Male, age 75, left hemisphere 524.7
2823 Male, age 76, right hemisphere 523.6
1865 Male, age 51, unknown 522.7
2503 Female, age 72, unknown 522.7
1954 Female, age 42, unknown 520.6
2588 Male, age 74, left hemisphere 520.6
1821 Female, age 72, unknown 520.3
2769 Male, age 72, unknown 515.9
2227 Male, age 72, unknown 514.9
1904 Male, age 53, unknown 509.3
Substantia nigra
nTPM: 533.4
1916 Female, age 42, unknown 562.7
1889 Female, age 72, unknown 550.8
2665 Male, age 74, both hemispheres 536.8
2241 Male, age 72, unknown 534.8
1941 Male, age 53, unknown 534.3
1851 Male, age 51, unknown 530.8
2409 Female, age 72, unknown 528.1
2699 Male, age 18, unknown 524.6
2590 Female, age 75, unknown 516.5
2583 Male, age 75, right hemisphere 514.3
Superior colliculus
nTPM: 519.1
2087 Female, age 72, unknown 535.5
1796 Male, age 53, unknown 526.9
1895 Male, age 76, right hemisphere 524.0
2668 Female, age 75, unknown 521.7
2587 Male, age 74, left hemisphere 521.3
2261 Male, age 18, unknown 520.5
1913 Female, age 42, unknown 516.3
1839 Male, age 51, unknown 511.0
1995 Male, age 72, unknown 507.1
2664 Male, age 75, both hemispheres 506.8
Ventral tegmental area
nTPM: 523.8
1915 Female, age 42, unknown 534.1
2218 Male, age 76, both hemispheres 531.8
1942 Male, age 51, unknown 526.3
2223 Female, age 72, unknown 525.4
2410 Female, age 72, unknown 513.7
2021 Male, age 53, unknown 511.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 517.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 517.1
Samples: 139

Max nTPM: 977.5
Min nTPM: 298.4
Std nTPM: 134.2
Median nTPM: 493.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 977.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 924.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 884.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 829.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 825.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 814.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 784.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 754.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 753.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 750.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 743.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 719.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 712.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 707.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 707.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 703.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 700.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 686.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 684.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 679.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 673.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 668.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 668.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 633.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 633.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 632.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 625.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 612.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 611.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 600.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 598.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 598.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 593.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 592.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 591.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 586.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 577.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 574.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 563.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 560.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 558.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 557.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 551.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 550.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 546.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 545.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 545.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 545.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 543.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 542.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 541.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 540.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 535.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 531.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 526.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 524.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 522.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 520.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 520.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 520.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 520.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 519.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 516.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 513.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 506.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 505.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 503.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 502.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 496.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 493.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 489.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 487.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 487.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 486.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 485.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 478.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 476.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 474.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 473.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 471.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 468.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 467.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 457.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 454.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 450.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 448.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 448.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 448.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 444.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 442.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 440.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 439.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 439.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 438.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 437.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 432.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 429.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 429.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 429.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 428.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 426.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 425.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 424.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 423.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 420.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 418.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 413.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 413.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 413.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 411.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 409.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 408.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 407.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 406.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 400.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 397.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 396.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 388.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 385.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 385.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 383.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 380.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 379.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 375.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 373.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 371.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 361.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 355.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 355.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 351.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 350.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 348.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 343.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 334.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 329.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 327.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 306.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 299.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 298.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 238.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 238.8
FF:10158-103A5 76 years, female 238.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 163.9
Pig sample Sample description nTPM
Midbrain
nTPM: 151.5
Samples: 4

Max nTPM: 173.4
Min nTPM: 135.6
Sample A Female 173.4
Sample B Female 149.5
Sample C Male 147.4
Sample D Male 135.6
Periaqueductal gray
nTPM: 116.7
Samples: 3

Max nTPM: 129.2
Min nTPM: 100.1
Sample B Female 129.2
Sample C Male 120.8
Sample D Male 100.1
Substantia nigra
nTPM: 139.8
Samples: 4

Max nTPM: 206.8
Min nTPM: 93.2
Sample A Female 206.8
Sample B Female 136.4
Sample C Male 122.9
Sample D Male 93.2
Superior colliculi
nTPM: 163.9
Samples: 4

Max nTPM: 203.2
Min nTPM: 137.1
Sample A Female 203.2
Sample B Female 139.9
Sample C Male 175.4
Sample D Male 137.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 441.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 441.2
Samples: 4

Max nTPM: 473.2
Min nTPM: 389.4
Sample A Male 467.1
Sample B Male 435.0
Sample C Female 389.4
Sample D Female 473.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.9
68076547 Antisense, RP_040923_02_F08, Mouse strain C57BL/6J (56 days, male) 1.5
70918976 Antisense, RP_050712_04_H06, Mouse strain C57BL/6J (56 days, male) 0.4

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