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MARCKSL1
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BRAIN WHITE MATTER Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
WHITE MATTER - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:712.7 nTPM
HPA:712.7 nTPM
FANTOM5:1250.3 Scaled Tags Per Million
Pig:1551.6 nTPM
Mouse:282.8 nTPM

WHITE MATTER - HPA Brain RNA-seq
Max nTPM 712.7
Sample id Sample description nTPM
Angular gyrus (white matter)
nTPM: 500.7
1920 Male, age 76, both hemispheres 500.7
Anterior funiculus (white matter)
nTPM: 586.2
2818 Female, age 79, both hemispheres 608.4
2193 Male, age 75, both hemispheres 595.2
2734 Male, age 80, both hemispheres 584.5
2819 Male, age 47, both hemispheres 556.7
Area striata (white matter)
nTPM: 500.3
2258 Female, age 91, left hemisphere 500.3
Cerebellar white matter
nTPM: 706.2
1864 Male, age 80, left hemisphere 765.0
1837 Male, age 76, left hemisphere 749.6
2773 Female, age 85, right hemisphere 730.8
1931 Female, age 91, left hemisphere 705.7
2174 Male, age 61, right hemisphere 664.2
2105 Male, age 74, right hemisphere 621.7
Corpus callosum, genu (white matter)
nTPM: 601.4
1887 Male, age 76, left hemisphere 866.6
1934 Male, age 61, right hemisphere 654.6
1886 Female, age 67, right hemisphere 635.8
1849 Female, age 91, right hemisphere 568.1
2771 Male, age 75, left hemisphere 493.6
1885 Female, age 94, left hemisphere 389.6
Corpus callosum, splenium (white matter)
nTPM: 561.7
2847 Female, age 67, right hemisphere 670.2
1946 Male, age 76, left hemisphere 650.0
2104 Male, age 75, left hemisphere 466.3
2238 Female, age 94, right hemisphere 460.4
Dorsal funiculus (white matter)
nTPM: 662.4
2810 Male, age 90, both hemispheres 798.7
2817 Male, age 47, both hemispheres 665.7
2128 Male, age 75, both hemispheres 655.3
2064 Female, age 79, both hemispheres 625.0
2812 Male, age 66, both hemispheres 567.5
Lateral funiculus (white matter)
nTPM: 581.3
2099 Male, age 90, both hemispheres 695.4
2094 Female, age 79, both hemispheres 610.0
2192 Male, age 75, both hemispheres 604.8
2294 Male, age 66, both hemispheres 415.0
Occipital cortex (white matter)
nTPM: 554.3
2259 Male, age 75, midline 612.7
2257 Female, age 67, both hemispheres 495.9
Parahippocampal cortex (white matter)
nTPM: 395.7
2157 Female, age 91, both hemispheres 395.7
Parieto-temporal junction (white matter)
nTPM: 712.7
2774 Male, age 61, right hemisphere 890.0
2121 Male, age 76, left hemisphere 846.3
1935 Female, age 94, right hemisphere 708.1
2770 Female, age 91, right hemisphere 652.5
1999 Female, age 67, right hemisphere 625.0
2469 Male, age 75, right hemisphere 554.3
Somatomor cortex, precentral gyrus (white matter)
nTPM: 366.2
2439 Male, age 75, right hemisphere 366.2
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 391.7
2623 Male, age 75, right hemisphere 391.7
Temporal white matter
nTPM: 602.7
2736 Female, age 91, right hemisphere 829.2
1801 Male, age 76, left hemisphere 624.4
2524 Female, age 85, left hemisphere 537.5
2254 Male, age 75, right hemisphere 535.1
2523 Female, age 94, left hemisphere 487.3

WHITE MATTER - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1250.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Corpus callosum
Scaled Tags Per Million: 1250.3
FF:10042-101F6 24-68 years, mixed 1250.3

WHITE MATTER - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1551.6
Pig sample Sample description nTPM
Corpus callosum
nTPM: 1551.6
Samples: 4

Max nTPM: 1631.7
Min nTPM: 1439.7
Sample A Female 1439.7
Sample B Female 1596.0
Sample C Male 1631.7
Sample D Male 1539.0

WHITE MATTER - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 282.8
Mouse sample Sample description nTPM
Corpus callosum
nTPM: 282.8
Samples: 3

Max nTPM: 328.2
Min nTPM: 250.7
Sample A Male 269.5
Sample B Male 250.7
Sample D Female 328.2

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by the Knut & Alice Wallenberg Foundation.