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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:3147.1 nTPM
HPA:3147.1 nTPM
FANTOM5:4214.7 Scaled Tags Per Million
Pig:414.2 nTPM
Allen mouse:10.0 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 3147.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 2882.7
2301 Female, age 85, both hemispheres 3126.9
2188 Female, age 91, both hemispheres 3078.8
2090 Male, age 80, both hemispheres 2879.6
1984 Male, age 76, both hemispheres 2445.4
Dorsal cochlear nucleus
nTPM: 2531.8
2187 Female, age 91, both hemispheres 2785.0
2378 Male, age 80, both hemispheres 2597.4
2370 Male, age 61, both hemispheres 2477.9
2802 Male, age 74, right hemisphere 2461.7
2058 Male, age 76, both hemispheres 2336.8
Dorsal tegmental nucleus
nTPM: 2703.5
2083 Male, age 80, both hemispheres 2931.2
2358 Male, age 61, both hemispheres 2904.6
2326 Male, age 74, both hemispheres 2564.6
1936 Male, age 76, left hemisphere 2413.5
Dorsolateral tegmental area
nTPM: 2669.1
2337 Male, age 61, both hemispheres 2977.3
2751 Female, age 85, both hemispheres 2955.1
2654 Male, age 80, both hemispheres 2817.1
2141 Male, age 76, both hemispheres 2304.0
2360 Male, age 74, both hemispheres 2292.0
Kolliker-Fuse nucleus
nTPM: 3020.3
2793 Female, age 91, left hemisphere 3268.2
2315 Male, age 76, right hemisphere 3112.5
2163 Male, age 80, both hemispheres 2680.2
Lateral lemniscal nuclei
nTPM: 2697.8
2320 Female, age 91, left hemisphere 2915.4
2746 Female, age 85, left hemisphere 2846.9
2036 Male, age 80, both hemispheres 2795.1
2453 Male, age 74, right hemisphere 2543.1
2169 Male, age 76, both hemispheres 2388.4
Lateral parabrachial nucleus
nTPM: 2810.4
2792 Male, age 76, both hemispheres 3314.9
2013 Male, age 80, both hemispheres 2833.7
2139 Female, age 85, right hemisphere 2605.3
2790 Male, age 61, both hemispheres 2487.8
Lateral vestibular nucleus
nTPM: 2600.4
2311 Male, age 80, both hemispheres 2774.2
2184 Male, age 76, both hemispheres 2426.7
Locus coeruleus
nTPM: 2284.5
2162 Male, age 80, both hemispheres 2381.7
2720 Male, age 74, both hemispheres 2333.9
2317 Female, age 72, unknown 2318.1
2123 Female, age 91, both hemispheres 2304.5
2788 Male, age 74, unknown 2264.6
2014 Male, age 55, unknown 2225.9
1980 Male, age 76, both hemispheres 2162.5
Medial olivary nucleus
nTPM: 3147.1
2851 Male, age 80, both hemispheres 3209.1
1943 Male, age 61, both hemispheres 3206.4
1962 Male, age 76, both hemispheres 3161.9
2138 Female, age 91, both hemispheres 3010.9
Medial parabrachial nucleus
nTPM: 2727.5
2854 Male, age 80, both hemispheres 2925.2
2170 Female, age 91, both hemispheres 2918.8
2463 Female, age 85, right hemisphere 2826.8
2156 Male, age 61, both hemispheres 2528.5
2786 Male, age 76, both hemispheres 2438.1
Medial periolivary nuclei
nTPM: 2696.5
2081 Male, age 80, both hemispheres 2987.0
2791 Male, age 74, right hemisphere 2819.1
2458 Female, age 91, both hemispheres 2804.7
2171 Female, age 85, both hemispheres 2436.5
2063 Male, age 76, both hemispheres 2435.2
Motor facial nucleus
nTPM: 2677.3
2697 Female, age 85, both hemispheres 2998.6
2365 Male, age 74, right hemisphere 2853.4
2126 Male, age 61, both hemispheres 2675.5
2327 Male, age 80, both hemispheres 2601.5
2795 Female, age 91, both hemispheres 2586.0
2062 Male, age 76, both hemispheres 2348.7
Motor trigeminal nucleus
nTPM: 2675.4
2079 Male, age 80, both hemispheres 2765.8
2321 Female, age 91, both hemispheres 2755.0
2560 Male, age 74, both hemispheres 2711.8
2335 Male, age 61, both hemispheres 2668.6
2309 Male, age 76, both hemispheres 2476.1
Nuclei of the trapezoid body
nTPM: 2541.5
2166 Male, age 80, both hemispheres 2837.9
2368 Female, age 91, both hemispheres 2630.9
1983 Male, age 76, both hemispheres 2476.7
2159 Male, age 61, both hemispheres 2424.2
2735 Female, age 85, both hemispheres 2338.0
Paramedian reticular nucleus
nTPM: 2606.3
2057 Male, age 80, both hemispheres 2687.7
2050 Female, age 85, both hemispheres 2678.2
2052 Male, age 76, both hemispheres 2603.9
2313 Male, age 61, both hemispheres 2455.4
Pontine nuclei
nTPM: 2769.1
2454 Male, age 74, left hemisphere 3117.4
2319 Female, age 91, both hemispheres 3020.2
2109 Female, age 72, unknown 2932.4
2115 Male, age 80, left hemisphere 2851.4
1863 Male, age 55, unknown 2774.5
2787 Female, age 85, both hemispheres 2605.0
1968 Male, age 76, left hemisphere 2482.9
2727 Male, age 61, right hemisphere 2368.9
Pontine raphe nucleus
nTPM: 2447.7
2122 Female, age 85, midline 2519.6
2853 Male, age 76, midline 2375.8
Posteroventral cochlear nucleus
nTPM: 2803.2
2135 Female, age 91, both hemispheres 3281.6
2341 Male, age 80, both hemispheres 3107.2
2371 Male, age 61, both hemispheres 2623.9
2070 Male, age 76, both hemispheres 2552.3
2752 Female, age 85, both hemispheres 2450.6
Principal sensory trigeminal nucleus
nTPM: 2584.1
2367 Female, age 91, left hemisphere 2978.1
2008 Male, age 80, left hemisphere 2557.0
2324 Male, age 76, both hemispheres 2438.3
2158 Male, age 61, both hemispheres 2362.9
Reticular pontine nucleus, caudal
nTPM: 2761.4
2457 Female, age 91, both hemispheres 2865.9
2559 Male, age 74, both hemispheres 2763.0
2332 Male, age 80, right hemisphere 2709.5
2092 Male, age 76, both hemispheres 2707.4
Reticular pontine nucleus, oral
nTPM: 2832.6
2366 Female, age 91, both hemispheres 3123.7
2361 Male, age 74, both hemispheres 2926.4
1939 Male, age 80, both hemispheres 2883.0
2012 Female, age 85, both hemispheres 2670.1
2167 Male, age 76, both hemispheres 2559.6
Reticulotegmental nucleus
nTPM: 2595.2
2333 Male, age 80, both hemispheres 2756.4
2322 Female, age 91, both hemispheres 2713.1
2452 Male, age 74, both hemispheres 2552.8
2325 Male, age 76, both hemispheres 2358.6
Spinal trigeminal nucleus, oral
nTPM: 2474.7
2164 Male, age 80, both hemispheres 2681.8
2737 Female, age 85, both hemispheres 2414.5
1978 Male, age 76, both hemispheres 2327.7
Subcoeruleus area
nTPM: 2608.1
2369 Female, age 85, left hemisphere 3133.6
1958 Male, age 80, both hemispheres 2688.0
2323 Female, age 91, left hemisphere 2469.8
2089 Male, age 76, left hemisphere 2426.5
2451 Male, age 74, both hemispheres 2322.8
Superior olive
nTPM: 2713.5
2329 Male, age 80, right hemisphere 2838.0
2364 Male, age 74, right hemisphere 2786.4
2561 Female, age 91, both hemispheres 2735.9
2020 Male, age 76, both hemispheres 2605.7
1875 Female, age 85, both hemispheres 2601.5
Superior vestibular nucleus
nTPM: 2518.1
2015 Male, age 80, both hemispheres 2604.2
2061 Male, age 76, both hemispheres 2505.9
2383 Male, age 74, both hemispheres 2444.3
Ventral periolivary nuclei
nTPM: 2574.9
2023 Male, age 76, both hemispheres 2744.1
2165 Male, age 80, both hemispheres 2635.3
2794 Female, age 91, left hemisphere 2495.0
2130 Female, age 85, both hemispheres 2425.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 2750.0
2840 Female, age 85, both hemispheres 3000.5
2161 Male, age 80, both hemispheres 2819.1
2456 Female, age 91, both hemispheres 2795.2
2359 Male, age 61, both hemispheres 2649.1
2449 Male, age 74, both hemispheres 2634.1
1959 Male, age 76, both hemispheres 2601.8

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 4214.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 4214.7
FF:10165-103B3 76 years, female 4795.6
FF:10182-103D2 60 years, female 3633.7
Pons
Scaled Tags Per Million: 3602.5
FF:10033-101E6 18-54 years, mixed 3602.5

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 414.2
Pig sample Sample description nTPM
Pons
nTPM: 414.2
Samples: 4

Max nTPM: 646.5
Min nTPM: 256.3
Sample A Female 359.1
Sample B Female 256.3
Sample C Male 395.0
Sample D Male 646.5

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 10.0
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 10.0
74357575 Antisense, RP_050927_03_A08, Mouse strain C57BL/6J (56 days, male) 10.0
72182998 Antisense, RP_050927_03_A08, Mouse strain C57BL/6J (56 days, male) 9.3

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.