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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:899.1 nTPM
HPA:899.1 nTPM
GTEx:945.8 nTPM
FANTOM5:278.5 Scaled Tags Per Million
Pig:0.3 nTPM
Mouse:258.9 nTPM
Allen mouse:4.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 899.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 887.6
2666 Male, age 74, left hemisphere 908.0
2411 Female, age 72, unknown 895.1
1870 Female, age 42, unknown 893.7
2828 Female, age 72, unknown 887.7
2019 Male, age 18, unknown 886.7
1827 Male, age 72, unknown 885.5
1833 Male, age 53, unknown 885.3
1830 Male, age 51, unknown 882.6
2586 Male, age 75, left hemisphere 876.0
2219 Male, age 76, both hemispheres 875.2
Dorsal raphe nucleus
nTPM: 886.4
2298 Female, age 72, unknown 895.6
1828 Male, age 53, unknown 890.1
2016 Female, age 72, unknown 884.7
2750 Male, age 76, both hemispheres 883.8
2047 Male, age 72, unknown 877.9
Inferior colliculus
nTPM: 886.2
2849 Male, age 72, unknown 889.8
1890 Male, age 53, unknown 887.8
2097 Female, age 72, unknown 886.2
1848 Female, age 42, unknown 880.9
Median raphe nucleus
nTPM: 886.4
2220 Male, age 76, midline 886.4
Pedunculopontine tegmental nucleus
nTPM: 891.8
2338 Male, age 61, both hemispheres 901.4
2334 Male, age 80, both hemispheres 895.9
1921 Female, age 85, both hemispheres 878.1
Periaquaductal grey, anterior
nTPM: 889.5
2502 Female, age 75, unknown 896.7
1947 Male, age 18, unknown 887.9
1795 Male, age 51, unknown 883.8
Periaquaductal grey, dorsal
nTPM: 889.4
1840 Male, age 53, unknown 904.4
2850 Male, age 76, both hemispheres 892.3
2464 Female, age 72, unknown 881.0
1831 Male, age 72, unknown 879.8
Periaquaductal grey, lateral
nTPM: 883.5
2140 Male, age 76, both hemispheres 889.2
2053 Male, age 18, unknown 883.1
2272 Male, age 74, both hemispheres 878.2
Pretectal area
nTPM: 884.9
1817 Female, age 42, unknown 892.5
2825 Male, age 18, unknown 892.5
1815 Male, age 53, unknown 888.8
1944 Female, age 72, unknown 888.4
2007 Male, age 72, unknown 886.6
2224 Female, age 72, unknown 886.2
1816 Male, age 51, unknown 883.8
2273 Male, age 74, both hemispheres 881.1
2316 Male, age 76, right hemisphere 881.0
2667 Female, age 75, unknown 876.8
2407 Male, age 75, both hemispheres 875.9
Red nucleus
nTPM: 898.9
2503 Female, age 72, unknown 924.6
2725 Female, age 75, unknown 916.0
1865 Male, age 51, unknown 906.1
2588 Male, age 74, left hemisphere 903.8
1821 Female, age 72, unknown 900.9
1904 Male, age 53, unknown 899.1
2227 Male, age 72, unknown 896.9
2769 Male, age 72, unknown 895.9
1954 Female, age 42, unknown 893.3
2785 Male, age 18, unknown 887.9
2584 Male, age 75, left hemisphere 887.0
2823 Male, age 76, right hemisphere 875.5
Substantia nigra
nTPM: 899.1
2409 Female, age 72, unknown 918.6
1851 Male, age 51, unknown 917.2
2241 Male, age 72, unknown 916.4
1916 Female, age 42, unknown 905.2
2699 Male, age 18, unknown 904.8
2665 Male, age 74, both hemispheres 904.7
1889 Female, age 72, unknown 887.9
2590 Female, age 75, unknown 885.2
1941 Male, age 53, unknown 878.8
2583 Male, age 75, right hemisphere 871.9
Superior colliculus
nTPM: 887.4
2587 Male, age 74, left hemisphere 915.7
1913 Female, age 42, unknown 893.8
1995 Male, age 72, unknown 889.0
1796 Male, age 53, unknown 885.9
2668 Female, age 75, unknown 885.8
2261 Male, age 18, unknown 885.0
2087 Female, age 72, unknown 882.4
1839 Male, age 51, unknown 882.2
1895 Male, age 76, right hemisphere 880.0
2664 Male, age 75, both hemispheres 874.5
Ventral tegmental area
nTPM: 894.0
1915 Female, age 42, unknown 908.3
2223 Female, age 72, unknown 902.7
2410 Female, age 72, unknown 892.8
2021 Male, age 53, unknown 890.5
1942 Male, age 51, unknown 886.6
2218 Male, age 76, both hemispheres 883.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 945.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 945.8
Samples: 139

Max nTPM: 3423.1
Min nTPM: 404.0
Std nTPM: 403.7
Median nTPM: 837.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3423.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2513.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2253.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2107.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1795.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1686.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1611.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1603.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1595.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1558.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1438.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1392.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1366.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1358.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1355.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1341.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1313.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1269.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1238.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1215.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1213.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1208.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1203.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1202.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1200.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1198.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1196.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1181.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1180.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1157.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1141.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1134.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1116.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1112.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1107.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1100.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1099.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1089.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1075.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1067.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1048.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1046.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1046.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1045.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1019.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 996.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 987.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 984.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 983.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 982.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 954.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 953.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 947.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 924.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 924.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 921.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 918.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 905.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 899.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 890.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 876.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 872.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 871.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 869.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 867.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 859.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 854.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 841.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 840.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 837.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 832.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 829.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 824.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 824.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 823.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 818.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 818.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 811.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 806.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 801.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 793.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 783.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 781.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 779.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 778.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 771.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 770.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 769.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 769.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 767.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 762.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 750.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 749.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 745.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 742.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 740.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 737.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 736.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 732.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 711.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 704.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 700.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 697.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 695.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 691.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 690.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 686.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 682.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 670.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 669.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 664.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 659.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 651.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 650.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 645.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 638.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 626.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 623.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 619.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 614.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 602.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 601.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 599.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 597.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 591.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 587.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 586.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 585.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 576.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 571.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 567.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 554.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 554.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 543.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 523.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 473.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 461.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 441.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 404.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 278.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 278.5
FF:10158-103A5 76 years, female 278.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 0.3
Pig sample Sample description nTPM
Midbrain
nTPM: 0.1
Samples: 4

Max nTPM: 0.2
Min nTPM: 0.1
Sample A Female 0.1
Sample B Female 0.1
Sample C Male 0.1
Sample D Male 0.2
Periaqueductal gray
nTPM: 0.3
Samples: 3

Max nTPM: 0.3
Min nTPM: 0.2
Sample B Female 0.2
Sample C Male 0.3
Sample D Male 0.3
Substantia nigra
nTPM: 0.1
Samples: 4

Max nTPM: 0.1
Min nTPM: 0.1
Sample A Female 0.1
Sample B Female 0.1
Sample C Male 0.1
Sample D Male 0.1
Superior colliculi
nTPM: 0.2
Samples: 4

Max nTPM: 0.3
Min nTPM: 0.1
Sample A Female 0.1
Sample B Female 0.1
Sample C Male 0.3
Sample D Male 0.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 258.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 259.0
Samples: 4

Max nTPM: 293.5
Min nTPM: 234.2
Sample A Male 293.5
Sample B Male 249.2
Sample C Female 234.2
Sample D Female 258.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.8
68498271 Antisense, RP_050113_01_F04, Mouse strain C57BL/6J (56 days, male) 4.8

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