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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:1108.8 nTPM
HPA:1108.8 nTPM
GTEx:1043.9 nTPM
FANTOM5:1441.6 Scaled Tags Per Million
Pig:1937.5 nTPM
Mouse:1349.5 nTPM
Allen mouse:24.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 1108.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 926.1
1827 Male, age 72, unknown 1028.0
2666 Male, age 74, left hemisphere 1027.7
2411 Female, age 72, unknown 957.3
2586 Male, age 75, left hemisphere 948.1
2828 Female, age 72, unknown 936.7
2219 Male, age 76, both hemispheres 925.0
1870 Female, age 42, unknown 922.3
2019 Male, age 18, unknown 869.9
1833 Male, age 53, unknown 824.2
1830 Male, age 51, unknown 821.9
Dorsal raphe nucleus
nTPM: 931.2
2750 Male, age 76, both hemispheres 1007.5
2298 Female, age 72, unknown 997.3
2047 Male, age 72, unknown 952.5
1828 Male, age 53, unknown 923.6
2016 Female, age 72, unknown 774.9
Inferior colliculus
nTPM: 815.8
2097 Female, age 72, unknown 836.0
2849 Male, age 72, unknown 825.2
1848 Female, age 42, unknown 813.2
1890 Male, age 53, unknown 788.8
Median raphe nucleus
nTPM: 1108.8
2220 Male, age 76, midline 1108.8
Pedunculopontine tegmental nucleus
nTPM: 1028.9
2338 Male, age 61, both hemispheres 1107.5
2334 Male, age 80, both hemispheres 1018.7
1921 Female, age 85, both hemispheres 960.4
Periaquaductal grey, anterior
nTPM: 997.9
1947 Male, age 18, unknown 1045.3
1795 Male, age 51, unknown 1036.5
2502 Female, age 75, unknown 911.9
Periaquaductal grey, dorsal
nTPM: 851.0
1840 Male, age 53, unknown 878.9
2850 Male, age 76, both hemispheres 873.8
2464 Female, age 72, unknown 826.4
1831 Male, age 72, unknown 824.7
Periaquaductal grey, lateral
nTPM: 816.3
2053 Male, age 18, unknown 864.5
2140 Male, age 76, both hemispheres 830.4
2272 Male, age 74, both hemispheres 754.0
Pretectal area
nTPM: 951.8
1816 Male, age 51, unknown 1181.2
1944 Female, age 72, unknown 1081.3
2007 Male, age 72, unknown 1070.9
1817 Female, age 42, unknown 1005.9
2667 Female, age 75, unknown 968.1
1815 Male, age 53, unknown 962.3
2224 Female, age 72, unknown 907.5
2825 Male, age 18, unknown 900.2
2407 Male, age 75, both hemispheres 832.7
2316 Male, age 76, right hemisphere 789.3
2273 Male, age 74, both hemispheres 770.5
Red nucleus
nTPM: 873.1
2584 Male, age 75, left hemisphere 939.7
1821 Female, age 72, unknown 932.1
2588 Male, age 74, left hemisphere 923.9
2725 Female, age 75, unknown 911.6
2503 Female, age 72, unknown 883.0
1954 Female, age 42, unknown 858.5
2785 Male, age 18, unknown 857.7
2227 Male, age 72, unknown 852.1
2769 Male, age 72, unknown 843.6
1865 Male, age 51, unknown 835.7
1904 Male, age 53, unknown 832.5
2823 Male, age 76, right hemisphere 806.8
Substantia nigra
nTPM: 977.8
1916 Female, age 42, unknown 1140.2
1941 Male, age 53, unknown 1071.3
1851 Male, age 51, unknown 1011.6
1889 Female, age 72, unknown 993.7
2590 Female, age 75, unknown 974.8
2241 Male, age 72, unknown 971.9
2665 Male, age 74, both hemispheres 962.6
2583 Male, age 75, right hemisphere 914.8
2409 Female, age 72, unknown 876.5
2699 Male, age 18, unknown 860.2
Superior colliculus
nTPM: 888.8
1796 Male, age 53, unknown 1021.9
2261 Male, age 18, unknown 989.8
2087 Female, age 72, unknown 985.0
2664 Male, age 75, both hemispheres 879.6
2668 Female, age 75, unknown 875.1
2587 Male, age 74, left hemisphere 857.8
1913 Female, age 42, unknown 856.1
1839 Male, age 51, unknown 845.2
1895 Male, age 76, right hemisphere 819.7
1995 Male, age 72, unknown 757.6
Ventral tegmental area
nTPM: 980.2
2218 Male, age 76, both hemispheres 1072.8
1915 Female, age 42, unknown 1026.7
2410 Female, age 72, unknown 1021.7
2223 Female, age 72, unknown 956.7
1942 Male, age 51, unknown 912.9
2021 Male, age 53, unknown 890.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1043.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1043.9
Samples: 139

Max nTPM: 3081.1
Min nTPM: 267.8
Std nTPM: 438.3
Median nTPM: 979.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 3081.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 2665.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 2129.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 2050.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1992.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1984.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1897.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1880.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1715.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1660.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1651.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 1650.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1648.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1595.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1548.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1516.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1504.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 1480.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1463.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1456.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1452.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1444.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1425.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1392.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1378.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1370.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1360.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1340.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1336.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1290.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1267.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1265.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1251.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1250.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1247.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1244.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1243.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1235.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1228.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1192.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1189.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1185.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1179.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1173.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1160.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1151.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1148.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1146.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1138.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1137.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1132.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1127.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1119.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1112.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1101.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1096.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1092.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1063.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1058.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1051.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1050.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1048.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1031.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1020.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1012.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1009.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1000.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 994.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 991.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 979.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 978.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 973.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 969.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 962.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 962.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 956.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 951.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 946.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 929.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 927.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 925.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 919.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 908.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 908.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 900.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 895.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 882.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 871.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 852.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 849.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 848.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 838.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 836.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 828.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 822.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 798.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 783.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 769.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 760.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 751.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 748.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 738.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 732.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 727.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 714.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 703.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 689.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 677.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 671.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 669.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 669.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 662.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 659.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 657.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 657.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 632.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 624.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 624.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 621.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 621.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 600.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 586.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 586.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 576.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 572.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 566.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 561.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 546.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 533.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 525.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 520.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 518.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 513.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 482.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 476.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 418.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 394.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 344.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 267.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1441.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1441.6
FF:10158-103A5 76 years, female 1441.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1937.5
Pig sample Sample description nTPM
Midbrain
nTPM: 1937.5
Samples: 4

Max nTPM: 2723.1
Min nTPM: 1248.8
Sample A Female 2723.1
Sample B Female 1738.6
Sample C Male 2039.6
Sample D Male 1248.8
Periaqueductal gray
nTPM: 1497.4
Samples: 3

Max nTPM: 1943.9
Min nTPM: 1159.9
Sample B Female 1388.3
Sample C Male 1943.9
Sample D Male 1159.9
Substantia nigra
nTPM: 1852.6
Samples: 4

Max nTPM: 2547.4
Min nTPM: 1213.0
Sample A Female 2336.8
Sample B Female 1313.3
Sample C Male 2547.4
Sample D Male 1213.0
Superior colliculi
nTPM: 1509.7
Samples: 4

Max nTPM: 2108.1
Min nTPM: 917.7
Sample A Female 1672.8
Sample B Female 917.7
Sample C Male 2108.1
Sample D Male 1340.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1349.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 1349.5
Samples: 4

Max nTPM: 1384.2
Min nTPM: 1286.3
Sample A Male 1348.6
Sample B Male 1384.2
Sample C Female 1286.3
Sample D Female 1379.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 24.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 24.2
77465048 Antisense, RP_070129_03_A07, Mouse strain C57BL/6J (56 days, male) 24.2

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