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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:1162.2 nTPM
HPA:1162.2 nTPM
FANTOM5:5816.1 Scaled Tags Per Million
Pig:2056.0 nTPM
Allen mouse:20.4 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 1162.2
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 971.9
2188 Female, age 91, both hemispheres 1079.7
2301 Female, age 85, both hemispheres 978.2
2090 Male, age 80, both hemispheres 959.7
1984 Male, age 76, both hemispheres 869.9
Dorsal cochlear nucleus
nTPM: 949.1
2187 Female, age 91, both hemispheres 1120.6
2370 Male, age 61, both hemispheres 930.1
2802 Male, age 74, right hemisphere 919.3
2058 Male, age 76, both hemispheres 904.1
2378 Male, age 80, both hemispheres 871.5
Dorsal tegmental nucleus
nTPM: 990.5
2358 Male, age 61, both hemispheres 1087.1
2083 Male, age 80, both hemispheres 1046.9
2326 Male, age 74, both hemispheres 944.8
1936 Male, age 76, left hemisphere 883.3
Dorsolateral tegmental area
nTPM: 944.1
2751 Female, age 85, both hemispheres 1047.8
2654 Male, age 80, both hemispheres 992.8
2337 Male, age 61, both hemispheres 933.3
2141 Male, age 76, both hemispheres 915.9
2360 Male, age 74, both hemispheres 830.6
Kolliker-Fuse nucleus
nTPM: 1061.0
2163 Male, age 80, both hemispheres 1145.0
2793 Female, age 91, left hemisphere 1103.9
2315 Male, age 76, right hemisphere 934.0
Lateral lemniscal nuclei
nTPM: 1108.3
2169 Male, age 76, both hemispheres 1296.7
2036 Male, age 80, both hemispheres 1166.0
2453 Male, age 74, right hemisphere 1045.2
2746 Female, age 85, left hemisphere 1027.8
2320 Female, age 91, left hemisphere 1005.9
Lateral parabrachial nucleus
nTPM: 994.8
2139 Female, age 85, right hemisphere 1137.7
2013 Male, age 80, both hemispheres 999.1
2790 Male, age 61, both hemispheres 960.6
2792 Male, age 76, both hemispheres 881.7
Lateral vestibular nucleus
nTPM: 1082.8
2184 Male, age 76, both hemispheres 1146.8
2311 Male, age 80, both hemispheres 1018.7
Locus coeruleus
nTPM: 1101.9
2123 Female, age 91, both hemispheres 1242.0
2014 Male, age 55, unknown 1225.4
2720 Male, age 74, both hemispheres 1107.0
2788 Male, age 74, unknown 1056.3
2317 Female, age 72, unknown 1053.5
1980 Male, age 76, both hemispheres 1034.1
2162 Male, age 80, both hemispheres 995.3
Medial olivary nucleus
nTPM: 955.3
2138 Female, age 91, both hemispheres 1020.5
2851 Male, age 80, both hemispheres 974.8
1962 Male, age 76, both hemispheres 927.3
1943 Male, age 61, both hemispheres 898.7
Medial parabrachial nucleus
nTPM: 1043.9
2170 Female, age 91, both hemispheres 1232.2
2854 Male, age 80, both hemispheres 1071.0
2156 Male, age 61, both hemispheres 1045.0
2786 Male, age 76, both hemispheres 938.8
2463 Female, age 85, right hemisphere 932.6
Medial periolivary nuclei
nTPM: 1064.5
2063 Male, age 76, both hemispheres 1284.9
2171 Female, age 85, both hemispheres 1129.6
2458 Female, age 91, both hemispheres 1001.6
2081 Male, age 80, both hemispheres 957.9
2791 Male, age 74, right hemisphere 948.3
Motor facial nucleus
nTPM: 1054.6
2062 Male, age 76, both hemispheres 1320.7
2365 Male, age 74, right hemisphere 1049.2
2327 Male, age 80, both hemispheres 1008.4
2697 Female, age 85, both hemispheres 1007.8
2795 Female, age 91, both hemispheres 1005.2
2126 Male, age 61, both hemispheres 936.2
Motor trigeminal nucleus
nTPM: 1035.5
2560 Male, age 74, both hemispheres 1096.7
2321 Female, age 91, both hemispheres 1063.2
2079 Male, age 80, both hemispheres 1047.9
2335 Male, age 61, both hemispheres 1010.7
2309 Male, age 76, both hemispheres 958.9
Nuclei of the trapezoid body
nTPM: 1160.8
2159 Male, age 61, both hemispheres 1374.4
1983 Male, age 76, both hemispheres 1260.7
2735 Female, age 85, both hemispheres 1154.1
2166 Male, age 80, both hemispheres 1031.3
2368 Female, age 91, both hemispheres 983.6
Paramedian reticular nucleus
nTPM: 1084.7
2050 Female, age 85, both hemispheres 1187.0
2057 Male, age 80, both hemispheres 1107.0
2313 Male, age 61, both hemispheres 1102.2
2052 Male, age 76, both hemispheres 942.8
Pontine nuclei
nTPM: 1162.2
1863 Male, age 55, unknown 1326.8
2787 Female, age 85, both hemispheres 1320.5
2727 Male, age 61, right hemisphere 1254.5
1968 Male, age 76, left hemisphere 1183.3
2109 Female, age 72, unknown 1137.6
2454 Male, age 74, left hemisphere 1075.5
2319 Female, age 91, both hemispheres 1042.6
2115 Male, age 80, left hemisphere 957.0
Pontine raphe nucleus
nTPM: 1101.5
2122 Female, age 85, midline 1182.0
2853 Male, age 76, midline 1020.9
Posteroventral cochlear nucleus
nTPM: 993.1
2752 Female, age 85, both hemispheres 1044.4
2341 Male, age 80, both hemispheres 1031.9
2135 Female, age 91, both hemispheres 998.1
2070 Male, age 76, both hemispheres 965.2
2371 Male, age 61, both hemispheres 926.0
Principal sensory trigeminal nucleus
nTPM: 1136.8
2158 Male, age 61, both hemispheres 1341.7
2008 Male, age 80, left hemisphere 1085.8
2324 Male, age 76, both hemispheres 1072.8
2367 Female, age 91, left hemisphere 1047.1
Reticular pontine nucleus, caudal
nTPM: 1058.6
2092 Male, age 76, both hemispheres 1191.4
2332 Male, age 80, right hemisphere 1038.7
2457 Female, age 91, both hemispheres 1023.1
2559 Male, age 74, both hemispheres 981.2
Reticular pontine nucleus, oral
nTPM: 1047.3
2361 Male, age 74, both hemispheres 1156.1
2012 Female, age 85, both hemispheres 1111.7
1939 Male, age 80, both hemispheres 1023.9
2366 Female, age 91, both hemispheres 980.8
2167 Male, age 76, both hemispheres 964.0
Reticulotegmental nucleus
nTPM: 1036.2
2325 Male, age 76, both hemispheres 1148.1
2322 Female, age 91, both hemispheres 1038.2
2452 Male, age 74, both hemispheres 996.1
2333 Male, age 80, both hemispheres 962.4
Spinal trigeminal nucleus, oral
nTPM: 1026.0
2164 Male, age 80, both hemispheres 1113.3
2737 Female, age 85, both hemispheres 1058.2
1978 Male, age 76, both hemispheres 906.4
Subcoeruleus area
nTPM: 1037.9
2323 Female, age 91, left hemisphere 1101.9
2089 Male, age 76, left hemisphere 1092.1
1958 Male, age 80, both hemispheres 1071.6
2369 Female, age 85, left hemisphere 966.5
2451 Male, age 74, both hemispheres 957.2
Superior olive
nTPM: 1050.7
1875 Female, age 85, both hemispheres 1149.0
2020 Male, age 76, both hemispheres 1129.4
2329 Male, age 80, right hemisphere 1007.9
2561 Female, age 91, both hemispheres 990.5
2364 Male, age 74, right hemisphere 976.9
Superior vestibular nucleus
nTPM: 950.3
2015 Male, age 80, both hemispheres 1055.3
2061 Male, age 76, both hemispheres 922.6
2383 Male, age 74, both hemispheres 872.8
Ventral periolivary nuclei
nTPM: 1082.2
2130 Female, age 85, both hemispheres 1113.9
2023 Male, age 76, both hemispheres 1105.7
2165 Male, age 80, both hemispheres 1102.0
2794 Female, age 91, left hemisphere 1007.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 1037.4
1959 Male, age 76, both hemispheres 1127.1
2840 Female, age 85, both hemispheres 1072.7
2449 Male, age 74, both hemispheres 1062.7
2161 Male, age 80, both hemispheres 1023.0
2456 Female, age 91, both hemispheres 977.8
2359 Male, age 61, both hemispheres 961.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 5816.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 2554.5
FF:10182-103D2 60 years, female 3210.3
FF:10165-103B3 76 years, female 1898.8
Pons
Scaled Tags Per Million: 5816.1
FF:10033-101E6 18-54 years, mixed 5816.1

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 2056.0
Pig sample Sample description nTPM
Pons
nTPM: 2056.0
Samples: 4

Max nTPM: 2264.1
Min nTPM: 1827.8
Sample A Female 1827.8
Sample B Female 1872.4
Sample C Male 2259.7
Sample D Male 2264.1

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 20.4
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 20.4
77465048 Antisense, RP_070129_03_A07, Mouse strain C57BL/6J (56 days, male) 20.4

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.