In a study led by researchers in the HPA and at Brunel University London, a novel method for automated annotation of immunohistochemistry images was developed for annotating cell type-specific protein expression of 8 different cell types in human testis. The work comprised 7848 images (corresponding to 2794 proteins) and the image classifier also provided a novel uncertainty metrics (called DeepHistoClass), for identification of manual annotation errors. The workflow can be implemented for other tissues or utilized in large-scale protein mapping efforts for sourcing high-quality data...Read more

In a new international project - the Human Uterus Cell Atlas (HUTER) - researchers from the Human Protein Atlas and three other European countries will create a single-cell and spatial reference map of the human uterus. The HUTER project has been funded 4 million Euro from the European Union program H2020, and will run for two years (2020-2021)...Read more

Spermatogenesis is the process where sperm are made, and it involves thousands of genes and proteins that are activated and repressed. The function of a large proportion of these genes and proteins remains unknown and testis harbors many "missing proteins" (MPs)...Read more

The fallopian tube mucosal layer is a simple columnar epithelium composed of secretory and ciliated epithelial cells, in order to provide the necessary environment for fertilization of the egg cell...Read more